Cisplatin and doxorubicin repress vascular endothelial growth factor expression and differentially down-regulate hypoxia-inducible factor I activity in human ovarian cancer cells
- Author
- DUYNDAM, Monique C. A1 ; VAN BERKEL, Maria P. A1 ; DORSMAN, Josephine C2 3 ; ROCKX, Davy A. P2 ; PINEDO, Herbert M1 ; BOUEN, Epie1
[1] Department of Medical Oncology, VU University medical center, De Boelelaan 1117, 1081 HV Amsterdam, Netherlands
[2] Department of Gynaecology and Obstetrics, VU University medical center, Amsterdam, Netherlands
[3] Center of Medical Systems Biology, Leiden, Netherlands - Source
Biochemical pharmacology. 2007, Vol 74, Num 2, pp 191-201, 11 p ; ref : 38 ref
- CODEN
- BCPCA6
- ISSN
- 0006-2952
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs; Physiology, morphology
- Publisher
- Elsevier Science, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- HIF-1;VEGF;Taxanes;Cisplatin;Doxorubicin;P53
- Keyword (fr)
- Antibiotique Anticancéreux Cancer ovaire Cellule tumorale Cisplatine Doxorubicine Facteur croissance endothélium vasculaire Facteur transcription HIF1 Homme Ovulation Tumeur maligne Inhibiteur de la topoisomérase II Agent alkylant Anthracyclines Appareil génital femelle pathologie DNA topoisomerase (ATP-hydrolysing) Enzyme Inhibiteur enzyme Isomerases Ovaire pathologie Platine II Complexe
- Keyword (en)
- Antibiotic Antineoplastic agent Ovary cancer Tumor cell Cisplatin Doxorubicin Vascular endothelium growth factor Transcription factor HIF1 Human Ovulation Malignant tumor Alkylating agent Anthracyclins Female genital diseases DNA topoisomerase (ATP-hydrolysing) Enzyme Enzyme inhibitor Isomerases Ovarian diseases Platinum II Complexes
- Keyword (es)
- Antibiótico Anticanceroso Cáncer del ovario Célula tumoral Cisplatino Doxorubicina Factor crecimiento endotelio vascular Factor transcripción HIF1 Hombre Ovulación Tumor maligno Agente alquilante Antraciclinas Aparato genital hembra patología DNA topoisomerase (ATP-hydrolysing) Enzima Inhibidor enzima Isomerases Ovario patología Platino II Complejo
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20C Female genital diseases / 002B20C02 Tumors
- Discipline
- General pharmacology Gynecology. Andrology. Obstetrics
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18879216
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bcp.2007.04.003 
https://dx.doi.org/10.1016/j.bcp.2007.04.003
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