Randomized, controlled, double-blind trial with ivermectin on Loa loa microfilaraemia : efficacy of a low dose (∼25 μg/kg) versus current standard dose (1 50 μg/kg)
- Author
- KAMGNO, Joseph1 ; PION, Sebastien D. S2 ; TEJIOKEM, Mathurin C3 ; TWUM-DANSO, Nana A. Y4 ; THYLEFORS, Björn4 ; BOUSSINESQ, Michel5
[1] National Onchocerciasis Task Force, Ministry of Public Health, BP 4794, Yaounde, Cameroon
[2] Department of Infectious Disease Epidemiology, Imperial College Faculty of Medicine, St Mary's Campus, Norfolk Place, London W2 1PG, United Kingdom
[3] Laboratoire d'Epidémiologie et de Santé Publique, Centre Pasteur du Cameroun, BP 1274, Yaoundé, Cameroon
[4] Mectizan Donation Program, 750 Commerce Drive, Suite 400, Decatur, GA 30030, United States
[5] Institut de Recherche pour le Développement (IRD), Département Sociétés et Santé, UR-024, 213 rue La Fayette, 75480 Paris, France - Source
Transactions of the Royal Society of Tropical Medicine and Hygiene. 2007, Vol 101, Num 8, pp 777-785, 9 p ; ref : 3/4 p
- CODEN
- TRSTAZ
- ISSN
- 0035-9203
- Scientific domain
- Hygiene and public health, epidemiology, occupational medicine; Tropical medicine
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Adverse effects Clinical controlled trial Ivermectin Loa loa Loiasis Onchocerciasis
- Keyword (fr)
- Anthelminthique Antiparasitaire Chimiothérapie Dose faible Effet secondaire Essai clinique Etude comparative Etude double insu Homme Ivermectine Loa loa Loase Microfilaire Médecine tropicale Onchocercose Parasitémie Randomisation Traitement Cameroun Filariose Helmintha Helminthiase Infection Invertebrata Lactone Macrocycle Nemathelminthia Nematoda Nématodose Oeil pathologie Parasitose Peau pathologie Afrique
- Keyword (en)
- Anthelmintic Parasiticide Chemotherapy Low dose Secondary effect Clinical trial Comparative study Double blind study Human Ivermectin Loa loa Loaiasis Microfilaria Tropical medicine Onchocerciasis Parasitemia Randomization Treatment Cameroon Filariosis Helmintha Helminthiasis Infection Invertebrata Lactone Macrocycle Nemathelminthia Nematoda Nematode disease Eye disease Parasitosis Skin disease Africa
- Keyword (es)
- Antihelmíntico Antiparasitario Quimioterapia Dosis débil Efecto secundario Ensayo clínico Estudio comparativo Estudio doble ciego Hombre Ivermectina Loa loa Loasis Microfilaria Medicina tropical Oncocercosis Parasitemia Aleatorización Tratamiento Camerun Filariosis Helmintha Helmintiasis Infección Invertebrata Lactona Macrociclo Nemathelminthia Nematoda Nematodosis Ojo patología Parasitosis Piel patología Africa
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05E Parasitic diseases / 002B05E03 Helminthic diseases / 002B05E03B Diseases caused by nematodes / 002B05E03B4 Filariases / 002B05E03B4A Loaiasis
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05E Parasitic diseases / 002B05E03 Helminthic diseases / 002B05E03B Diseases caused by nematodes / 002B05E03B4 Filariases / 002B05E03B4C Onchocercosis
- Discipline
- Infectious pathology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18890130
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.trstmh.2007.03.018 
https://dx.doi.org/10.1016/j.trstmh.2007.03.018
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