Rapamycin reduces CCR5 density levels on CD4 T cells, and this effect results in potentiation of enfuvirtide (T-20) against R5 strains of human immunodeficiency virus type 1 in vitro
- Author
- HEREDIA, Alonso1 ; GILLIAM, Bruce1 ; LATINOVIC, Olga1 ; LE, Nhut1 ; BAMBA, Douty1 ; DEVICO, Anthony1 ; MELIKYAN, Gregory B1 ; GALLO, Robert C1 ; REDFIELD, Robert R1
[1] Institute of Human Virology, University of Maryland Biotechnology Institute, Baltimore, Maryland 21201, United States - Source
Antimicrobial agents and chemotherapy. 2007, Vol 51, Num 7, pp 2489-2496, 8 p ; ref : 45 ref
- CODEN
- AACHAX
- ISSN
- 0066-4804
- Scientific domain
- Microbiology, infectious diseases; Pharmacology drugs
- Publisher
- American Society for Microbiology, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antibactérien Antibiotique Anticancéreux Antirétroviral Antiviral Chimiokine CC Densité Enfuvirtide Immunodépresseur In vitro Potentialisation Récepteur chimiokine CCR5 Récepteur chimiokine SIDA Sirolimus Souche Virus HIV1 Inhibiteur de fusion Lymphocyte T CD4 Immunodéficit Immunopathologie Infection Inhibiteur synthèse protéique Lactone Lentivirus Macrocycle Macrolide Peptide Retroviridae Virose Virus immunodéficience humaine Virus
- Keyword (en)
- Antibacterial agent Antibiotic Antineoplastic agent Antiretroviral agent Antiviral CC chemokine Density Enfuvirtide Immunosuppressive agent In vitro Potentiation CCR5 chemokine receptor Chemokine receptor AIDS Sirolimus Strain HIV-1 virus CD4 T lymphocyte Immune deficiency Immunopathology Infection Protein synthesis inhibitor Lactone Lentivirus Macrocycle Macrolide Peptides Retroviridae Viral disease Human immunodeficiency virus Virus
- Keyword (es)
- Antibacteriano Antibiótico Anticanceroso Antiretroviral Antiviral Quimioquina CC Densidad Enfuvirtida Inmunodepresor In vitro Potencialización Receptor quimioquina CCR5 Receptor quimioquina SIDA Sirolimús Cepa HIV-1 virus Linfocito T CD4 Inmunodeficiencia Inmunopatología Infección Inhibidor síntesis proteica Lactona Lentivirus Macrociclo Macrólido Péptido Retroviridae Virosis Human immunodeficiency virus Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05C Viral diseases / 002B05C02 Human viral diseases / 002B05C02D Viral diseases of the lymphoid tissue and the blood. Aids
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B06 Immunopathology / 002B06D Immunodeficiencies. Immunoglobulinopathies / 002B06D01 Immunodeficiencies
- Discipline
- Immunopathology Infectious pathology Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18894011
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1128/AAC.01602-06 
https://dx.doi.org/10.1128/AAC.01602-06
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