Dichloroacetate stabilizes the mutant E1α subunit in pyruvate dehydrogenase deficiency
- Author
- MORTEN, K. J1 ; BEATTIE, P1 ; BROWN, G. K2 ; MATTHEWS, P. M1
[1] Neurosciences Group, Institute of Molecular Medicine, Department of Clinical Neurology, University of Oxford, Oxford, United Kingdom
[2] Department of Biochemistry, University of Oxford, Oxford, United Kingdom - Source
Neurology. 1999, Vol 53, Num 3, pp 612-616 ; ref : 28 ref
- Publisher
- Lippincott Williams & Wilkins, Hagerstown, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité enzymatique Déficit Homme Lignée cellulaire Pyruvate dehydrogenase (NADP+) Traitement Acide dichloroacétique Enzyme Enzymopathie Maladie dégénérative Maladie héréditaire Métabolisme pathologie Oxidoreductases Système nerveux pathologie
- Keyword (en)
- Enzymatic activity Deficiency Human Cell line Pyruvate dehydrogenase (NADP+) Treatment Enzyme Enzymopathy Degenerative disease Genetic disease Metabolic diseases Oxidoreductases Nervous system diseases
- Keyword (es)
- Actividad enzimática Déficiencia Hombre Línea celular Pyruvate dehydrogenase (NADP+) Tratamiento Enzima Enzimopatía Enfermedad degenerativa Enfermedad hereditaria Metabolismo patología Oxidoreductases Sistema nervioso patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B22 Metabolic diseases / 002B22D Errors of metabolism / 002B22D03 Carbohydrates (enzymatic deficiencies). Glycogenosis
- Discipline
- Metabolic diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1891451
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1212/WNL.53.3.612 
https://dx.doi.org/10.1212/WNL.53.3.612
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