A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease
- Author
- BUCH, Stephan1 2 3 ; SCHAFMAYER, Clemens3 4 ; FRANCISCO MIQUEL, Juan9 ; NERVI, Flavio9 ; WITTIG, Michael2 ; ROSSKOPF, Dieter10 ; TIMM, Birgit3 ; HÖLL, Christine3 ; SEEGER, Marcus1 ; ELSHARAWY, Abdou2 ; LU, Tim11 ; EGBERTS, Jan4 ; VÖLZKE, Henry5 ; FANDRICH, Fred4 ; FÖLSCH, Ulrich R1 ; KRAWCZAK, Michael11 3 ; SCHREIBER, Stefan2 3 ; NÜRNBERG, Peter12 6 ; TEPEL, Jurgen4 ; HAMPE, Jochen1 ; BECKER, Christian6 7 ; FRANKE, Andre2 ; VON ELLER-EBERSTEIN, Huberta3 ; KLUCK, Christian6 7 ; BÄSSMANN, Ingelore6 7 ; BROSCH, Mario1 ; LAMMERT, Frank8
[1] First Department of Medicine, University Hospital Schleswig-Holstein, 24105 Kiel, Germany
[2] Institute for Clinical Molecular Biology, University Hospital Schleswig-Holstein, 24105 Kiel, Germany
[3] POPGEN Biobank, University Hospital Schleswig-Holstein, 24105 Kiel, Germany
[4] Department of General and Thoracic Surgery, University Hospital Schleswig-Holstein, 24105 Kiel, Germany
[5] Institute for Community Medicine, University Hospital Greifswald, Walther Rathenau Str. 48, 17487 Greifswald, Germany
[6] Cologne Center for Genomics, University of Cologne, Zülpicher Strasse 47, 50674 Cologne, Germany
[7] RZPD German Resource Center for Genome Research, Heubnerweg 6, 14059 Berlin, Germany
[8] Department of Internal Medicine I, University Hospital Bonn, Sigmund Freud-Strasse 25, 53105 Bonn, Germany
[9] Departamento de Gastroenterologia, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile
[10] Institute of Pharmacology, Ernst-Moritz-Arndt University Greifswald, Friedrich Loeffler Str. 23d, 17487 Greifswald, Germany
[11] Institute of Medical Statistics and Informatics, University Hospital Schleswig-Holstein, 24105 Kiel, Germany
[12] Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph -Stelzmann -Strasse 52, 50931 Köln, Germany - Source
Nature genetics. 2007, Vol 39, Num 8, pp 995-999, 5 p ; ref : 30 ref
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Cholestérol Génome Homme Identification Lithiase vésiculaire Association génétique Appareil digestif pathologie Lipide Voie biliaire pathologie
- Keyword (en)
- Cholesterol Genome Human Identification Cholelithiasis Digestive diseases Lipids Biliary tract disease
- Keyword (es)
- Colesterol Genoma Hombre Identificación Litiasis vesicular Aparato digestivo patología Lípido Vía biliar patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13C Liver. Biliary tract. Portal circulation. Exocrine pancreas / 002B13C03 Other diseases. Semiology
- Discipline
- Eukaryotes genetics. Biological and molecular evolution Gastroenterology. Liver. Pancreas. Abdomen
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18948976
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/ng2101 
https://dx.doi.org/10.1038/ng2101
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