Molecular targets and early response biomarkers for the prediction of developmental toxicity in vitro
- Author
- STIGSON, Michael1 ; KULTIMA, Kim1 ; JERGIL, Mans1 ; SCHOLZ, Birger1 ; AIM, Henrik1 ; GUSTAFSON, Anne-Lee2 ; DENCKER, Lennart1
[1] Department of Pharmaceutical Biosciences, Division of Toxicology, Uppsala University, Sweden
[2] Safety Assessment, AstraZeneca R&D, Södertälje, Sweden - Conference name
- Annual Workshop of the Scandinavian Society for Cell Toxicology (24 ; Stockholm 2006-09-07)
- Source
ATLA. Alternatives to laboratory animals. 2007, Vol 35, Num 3, pp 335-342, 8 p ; ref : 48 ref
- ISSN
- 0261-1929
- Scientific domain
- Medical laboratory techniques; Toxicology
- Publisher
- Fund for the Replacement of Animals in Medical Experiments, Nottingham
- Publication country
- United Kingdom
- Document type
- Conference Paper
- Language
- English
- Author keyword
- P19 mouse embryocarcinoma cells embryo microarray neural tube defect valproic acid
- Keyword (fr)
- Acide valproïque Animal Anticonvulsivant Dysraphie tube neural Embryon Facteur prédictif In vitro Marqueur biologique Méthode alternative Normothymique Précoce Prédiction Puce à DNA Souris Toxicité Tératogenèse Test tératogénicité 4-Aminobutyrate transaminase Enzyme Inhibiteur enzyme Malformation Mammalia Rachis pathologie Rodentia Système nerveux pathologie Système ostéoarticulaire pathologie Transaminases Transferases Vertebrata
- Keyword (en)
- Valproic acid Animal Anticonvulsant Neural tube defect Embryo Predictive factor In vitro Biological marker Alternative method Mood stabilizer Early Prediction DNA chip Mouse Toxicity Teratogenesis 4-Aminobutyrate transaminase Enzyme Enzyme inhibitor Malformation Mammalia Spine disease Rodentia Nervous system diseases Diseases of the osteoarticular system Transaminases Transferases Vertebrata
- Keyword (es)
- Acido valproico Animal Anticonvulsivante Disrafia tubo neural Embrión Factor predictivo In vitro Marcador biológico Método alternativo Estabilizador humor Precoz Predicción Pulga de DNA Ratón Toxicidad Teratogenesis 4-Aminobutyrate transaminase Enzima Inhibidor enzima Malformación Mammalia Raquis patología Rodentia Sistema nervioso patología Sistema osteoarticular patología Transaminases Transferases Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A30 Embryology: invertebrates and vertebrates. Teratology / 002A30E Teratology. Teratogens
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03A General aspects. Methods
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B15 Diseases of the osteoarticular system / 002B15F Diseases of the spine
- Discipline
- Embryology : invertebrates and vertebrates. Teratology Osteoarticular pathology Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18973177
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1177/026119290703500313 
https://dx.doi.org/10.1177/026119290703500313
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