Complete knockdown of CCR5 by lentiviral vector-expressed siRNAs and protection of transgenic macrophages against HIV-1 infection
- Author
- ANDERSON, J1 ; AKKINA, R1
[1] Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, United States - Source
Gene therapy (Basingstoke). 2007, Vol 14, Num 17, pp 1287-1297, 11 p ; ref : 52 ref
- ISSN
- 0969-7128
- Scientific domain
- Biotechnology; Genetics; Pharmacology drugs
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- CCR5 siRNAs CD34+ cells HIV-1 co-receptors HIV/AIDS gene therapy Lentiviral vector transgenic macrophages
- Keyword (fr)
- Expression génique Lentivirus Macrophage Protection Récepteur biologique SIDA Silence expression génique Thérapie génique Vecteur siRNA Interférence ARN Immunodéficit Immunopathologie Infection Retroviridae Virose Virus
- Keyword (en)
- Gene expression Lentivirus Macrophage Protection Biological receptor AIDS Gene silencing Gene therapy Vector Small Interference RNA RNA interference Immune deficiency Immunopathology Infection Retroviridae Viral disease Virus
- Keyword (es)
- Expresión genética Lentivirus Macrófago Protección Receptor biológico SIDA Silencio expresión genética Terapia génica Vector siRNA ARN interferencia Inmunodeficiencia Inmunopatología Infección Retroviridae Virosis Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A31 Biotechnology / 002A31D Industrial applications and implications. Economical aspects / 002A31D01 Health. Pharmaceutical industry / 002A31D01D Gene therapy
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05C Viral diseases / 002B05C02 Human viral diseases / 002B05C02D Viral diseases of the lymphoid tissue and the blood. Aids
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B27 Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy / 002B27D Transfusions. Complications. Transfusion reactions. Cell and gene therapy / 002B27D03 Applied cell therapy and gene therapy
- Discipline
- Anaesthesia. Reanimation. Transfusion. Cell therapy and gene therapy Biotechnology Infectious pathology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18980444
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.gt.3302958 
https://dx.doi.org/10.1038/sj.gt.3302958
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