Sponge-derived fijianolide polyketide class : Further evaluation of their structural and cytotoxicity properties
- Author
- JOHNSON, Tyler A1 ; TENNEY, Karen1 ; CREWS, Phillip1 ; CICHEWICZ, Robert H1 ; MORINAKA, Brandon I1 ; WHITE, Kimberly N1 ; AMAGATA, Taro1 ; SUBRAMANIAN, Balanehru2 ; MEDIA, Joseph2 ; MOOBERRY, Susan L3 ; VALERIOTE, Frederick A2
[1] Department of Chemistry and Biochemistry and Institute for Marine Sciences, University of California, Santa Cruz, California 95064, Josephine, United States
[2] Ford Cancer Center, Henry Ford Health System, Detroit, Michigan 48202, United States
[3] Southwest Foundation for Biomedical Research, San Antonio, Texas 78245, United States - Source
Journal of medicinal chemistry (Print). 2007, Vol 50, Num 16, pp 3795-3803, 9 p ; ref : 49 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Acétal Analyse structurale Animal Anticancéreux Antimitotique Cellule tumorale Chimiothérapie Composé tricyclique Cycle 6 chaînons Cytotoxicité Côlon Dérivé du pyrane Epoxyde Glande mammaire Glycol Homme Hémiacétal Hétérocycle oxygène In vitro In vivo Isolement Lactone Lignée cellulaire Milieu marin Origine animale Pathologie de la glande mammaire Pathologie expérimentale Pharmacocinétique Pharmacognosie Polycétide Porifera Souris Tumeur maligne Tumeur solide Voie intraveineuse Cacospongia mycofijiensis Fijianolide Lignée HCT116 Lignée MDAMB435 Vanuatu Cancer Invertebrata Mammalia Rodentia Traitement Vertebrata Mélanésie Océanie
- Keyword (en)
- Biological activity Acetal Structural analysis Animal Antineoplastic agent Antimitotic Tumor cell Chemotherapy Tricyclic compound Six membered ring Cytotoxicity Colon Pyran derivatives Epoxide Mammary gland Glycol Human Hemiacetal Oxygen heterocycle In vitro In vivo Isolation Lactone Cell line Marine environment Animal origin Mammary gland diseases Experimental disease Pharmacokinetics Pharmacognosy Polyketide Porifera Mouse Malignant tumor Solid tumor Intravenous administration Vanuatu Cancer Invertebrata Mammalia Rodentia Treatment Vertebrata Melanesia Oceania
- Keyword (es)
- Actividad biológica Acetal Análisis estructural Animal Anticanceroso Antimitótico Célula tumoral Quimioterapia Compuesto tricíclico Ciclo 6 eslabones Citotoxicidad Colón Pirano derivado Epóxido Glándula mamaria Glicol Hombre Hemiacetal Heterociclo oxígeno In vitro In vivo Aislamiento Lactona Línea celular Medio marino Origen animal Glándula mamaria patología Patología experimental Farmacocinética Farmacognosia Policetido Porifera Ratón Tumor maligno Tumor sólido Vía intravenosa Vanuatu Cáncer Invertebrata Mammalia Rodentia Tratamiento Vertebrata Melanesia Oceania
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A04 Pharmacognosy. Homeopathy. Health food
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18986616
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm070410z 
https://dx.doi.org/10.1021/jm070410z
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