MGMT : Key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents
- Author
- KAINA, Bernd1 ; CHRISTMANN, Markus1 ; NAUMANN, Steffen1 ; ROOS, Wynand P1
[1] Department of Toxicology, University of Mainz, Obere Zahlbacher Str. 67, 55131 Mainz, Germany - Issue title
- MGMT: REVERSAL OF FORTUNE. From basic biochemistry to clinical exploitation of the DNA damage reversal protein, O6-methylguanine-DNA methyltransferase
- Author (monograph)
- KAINA, Bernd (Editor)1 ; MARGISON, Geoffrey P (Editor)2
[1] Department of Toxicology, University of Mainz, Mains, Germany
[2] Paterson Institute for Cancer Research, Manchester, United Kingdom - Source
DNA repair. 2007, Vol 6, Num 8, pp 1079-1099, 21 p ; ref : 217 ref
- ISSN
- 1568-7864
- Scientific domain
- Biochemistry, molecular biology, biophysics; Genetics
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- MGMT,Genotoxicity,Carcinogenicity,Alkyltransferase,Temozolomide,Carmustine,Drug resistance,Alkylating agents,Tumor therapy
- Keyword (fr)
- Agent alkylant Anticancéreux Apoptose Carmustine DNA Génotoxicité Médicament Réparation Résistance Tumeur Témozolomide Toxicité
- Keyword (en)
- Alkylating agent Antineoplastic agent Apoptosis Carmustine DNA Genotoxicity Drug Repair Resistance Tumor Temozolomide Toxicity
- Keyword (es)
- Agente alquilante Anticanceroso Apoptosis Carmustina DNA Genotoxicidad Medicamento Reparación Resistencia Tumor Temozolomida Toxicidad
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04C Molecular genetics / 002A04C07 Mutagenesis. Repair
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H05 Ageing, cell death
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05B Bacteriology / 002A05B05 Growth, nutrition, cell differenciation
- Discipline
- Microbiology Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18987042
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.dnarep.2007.03.008 
https://dx.doi.org/10.1016/j.dnarep.2007.03.008
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