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Interleukin-6-dependent survival of multiple myeloma cells involves the stat3-mediated induction of microRNA-21 through a highly conserved enhancer. Commentary

Author
HURT, Elaine M (Commentator (written text)) 1 ; FARRAR, William L2 ; BLUMERT, Conny2 ; BAUER, Kay2 3 ; CVIJIC, Helena2 ; ULLMANN, A. Kerstin2 ; STADLER, Peter F4 5 ; HORN, Friedemann2 3 5 ; LÖFFLER, Dennis2 3 ; BROCKE-HEIDRICH, Katja2 3 ; PFEIFER, Gabriele2 ; STOCSITS, Claudia4 ; HACKERMÜLLER, Jörg5 ; KRETZSCHMAR, Antje K5 ; BURGER, Renate6 ; GRAMATZKI, Martin6
[1] NATIONAL CANCER INSTITUTE, United States
[2] Institute of Clinical Immunology and Transfusion Medicine, Medical Faculty, University of Leipzig, Leipzig, Germany
[3] Interdisciplinary Center for Clinical Studies, University of Leipzig, Germany
[4] Bioinformatics Group, Department of Computer Science, University of Leipzig, Leipzig, Germany
[5] Fraunhofer Institute of Cell Therapy and Immunology, Leipzig, Germany
[6] Division of Stem Cell Transplantation and Immunotherapy, 2nd Medical Department, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany
Source

Blood. 2007, Vol 110, Num 4 ; 1086-1087, 1330-1333 [6 p.] ; ref : 30 ref

ISSN
0006-4971
Scientific domain
Medical oncology; Hematology
Publisher
The Americain Society of Hematology, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Carcinogenèse Facteur transcription STAT3 Interleukine 6 Multiplication cellulaire Myélome Pathogénie Transduction signal Interférence ARN Survie cellulaire microARN Cytokine Hémopathie maligne Immunoglobulinopathie Immunopathologie Lymphoprolifératif syndrome
Keyword (en)
Carcinogenesis Transcription factor STAT3 Interleukin 6 Cell proliferation Myeloma Pathogenesis Signal transduction RNA interference Cell survival microRNA Cytokine Malignant hemopathy Immunoglobulinopathy Immunopathology Lymphoproliferative syndrome
Keyword (es)
Carcinogénesis Factor transcripción STAT3 Interleuquina 6 Multiplicación celular Mieloma Patogenia Transducción señal ARN interferencia Supervivencia celular miARN Citoquina Hemopatía maligna Inmunoglobulinopatía Inmunopatología Linfoproliferativo síndrome
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B06 Immunopathology / 002B06D Immunodeficiencies. Immunoglobulinopathies / 002B06D02 Immunoglobulinopathies

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis

Discipline
Blood diseases Immunopathology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
18993958

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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