Randomized placebo controlled phase I/II trial of α-galactosylceramide for the treatment of chronic hepatitis C
- Author
- VELDT, Bart J1 ; VAN DER VLIET, Hans J. J2 ; JANSSEN, Harry L. A1 ; VAN NIEUWKERK, Carin M. J8 ; VON BLOMBERG, B. Mary E3 ; VAN VLIERBERGHE, Hans4 ; GERKEN, Guido5 ; NISHI, Nobusuke6 ; HAYASHI, Kunihiko6 ; SCHEPER, Rik J3 ; DE KNEGT, Robert J1 ; VAN DEN EERTWEGH, Alfons J. M7
[1] Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Room Ca 326a, P.O. Box 2040, 3000 CA Rotterdam, Netherlands
[2] Department of Internal Medicine, Vrije Universiteit Medical Center, Amsterdam, Netherlands
[3] Department of Pathology, Vrije Universiteit Medical Center, Amsterdam, Netherlands
[4] Department of Gastroenterology and Hepatology, Ghent University Hospital, Ghent, Belgium
[5] Klinik für Gastroenterologie und Hepatologie, Universitätsklinikum Essen, Essen, Germany
[6] Pharmaceutical Division, Kirin Brewery Co. Ltd, Tokyo, Japan
[7] Department of Oncology, Vrije Universiteit Medical Center, Amsterdam, Netherlands
[8] Department of Gastroenterology and Hepatology, Vrije Universiteit Medical Center, Amsterdam, Netherlands - Source
Journal of hepatology. 2007, Vol 47, Num 3, pp 356-365, 10 p ; ref : 22 ref
- CODEN
- JOHEEC
- ISSN
- 0168-8278
- Scientific domain
- Gastroenterology
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Chronic hepatitis C Immunotherapy Interferon KRN7000 Natural killer T cells Non- responder α-GalCer
- Keyword (fr)
- Antiviral Cellule NK Essai clinique phase I Essai clinique phase II Homme Hépatite virale C Immunothérapie Interféron Lymphocyte T Ribavirine Toxicité Traitement Inhibiteur de linosine monophosphate déshydrogénase Analogue nucléoside Appareil digestif pathologie Cytokine Exploration immunologique Foie pathologie Infection Virose
- Keyword (en)
- Antiviral Natural killer cell Phase I trial Phase II trial Human Viral hepatitis C Immunotherapy Interferon T-Lymphocyte Ribavirin Toxicity Treatment Nucleoside analog Digestive diseases Cytokine Immunological investigation Hepatic disease Infection Viral disease
- Keyword (es)
- Antiviral Célula NK Ensayo clínico fase I Ensayo clínico fase II Hombre Hepatitis virica C Inmunoterapia Interferón Linfocito T Ribavirina Toxicidad Tratamiento Análogo nucleósido Aparato digestivo patología Citoquina Análisis inmunológico Hígado patología Infección Virosis
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S05 Antiviral agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05C Viral diseases / 002B05C02 Human viral diseases / 002B05C02G Viral hepatitis
- Discipline
- Infectious pathology Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 19005793
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.jhep.2007.04.018 
https://dx.doi.org/10.1016/j.jhep.2007.04.018
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