Chromatography of proteins on charge-variant ion exchangers and implications for optimizing protein uptake rates
- Author
- LANGFORD, John F1 ; XUANKUO XU1 ; YAN YAO1 ; MALONEY, Sean F1 ; LENHOFF, Abraham M1
[1] Department of Chemical Engineering, University of Delaware, Newark, DE 19716, United States - Source
Journal of chromatography. 2007, Vol 1163, Num 1-2, pp 190-202, 13 p ; ref : 65 ref
- CODEN
- JOCRAM
- ISSN
- 0021-9673
- Scientific domain
- Biochemistry, molecular biology, biophysics; Analytical chemistry; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Breakthrough Dynamic capacity Lysozyme Protein diffusion Protein uptake Ribonuclease A
- Keyword (fr)
- Capacité fixation Chromatographie échange ion Condition isocratique Courbe rupture Dimension particule Distribution dimension particule Echangeur cation Facteur rétention Isotherme adsorption Lysozyme Méthode séparation Optimisation Pancreatic ribonuclease Phase stationnaire Protéine basique Enzyme Esterases Glycosidases Hydrolases O-Glycosidases
- Keyword (en)
- Binding capacity Ion exchange chromatography Isocratic condition Breakthrough curve Particle size Particle size distribution Cation exchanger Retention factor Adsorption isotherm Lysozyme Separation method Optimization Pancreatic ribonuclease Stationary phase Basic protein Enzyme Esterases Glycosidases Hydrolases O-Glycosidases
- Keyword (es)
- Capacidad de fijación Cromatografía cambio iónico Condición isocrática Curva ruptura Dimensión partícula Distribución dimensión partícula Cambiador catiónico Factor retención Isotermo adsorción Lysozyme Método separación Optimización Pancreatic ribonuclease Fase estacionaria Proteína básica Enzima Esterases Glycosidases Hydrolases O-Glycosidases
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry / 002A02D Proteins / 002A02D01 General aspects, investigation methods
- Discipline
- Analytical, structural and metabolic biochemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 19011561
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.chroma.2007.06.028 
https://dx.doi.org/10.1016/j.chroma.2007.06.028
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