Synthesis of specific bivalent probes that functionally interact with 5-HT4 receptor dimers
- Author
- RUSSO, Olivier1 ; BERTHOUZE, Magali1 2 ; GINER, Mireille1 ; SOULIER, Jean-Louis1 ; RIVAIL, Lucie1 ; SICSIC, Sames1 ; LEZOUALC'H, Frank1 2 ; JOCKERS, Ralf3 4 ; BERQUE-BESTEL, Isabelle1
[1] Université Paris-Sud, Faculté de Pharmacie, IFR141, UMR-S769, Châtenay-Malabry, 92296, France
[2] Molécules Fluorées et Chimie Mddicinale and Inserm, U769, Signalisation et Physiopathologie Cardiaque, Chatenay-Malabry, 92296, France
[3] Inserm, U567, Department of Cell Biology, Paris, France
[4] Université Paris-Descartes, UMR-8104, Paris, France - Source
Journal of medicinal chemistry (Print). 2007, Vol 50, Num 18, pp 4482-4492, 11 p ; ref : 47 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Affinité Carboxamide Composé acétylénique Composé aliphatique Dimère Dérivé de la triazine Dérivé du benzène Dérivé du cyclohexane Fixation biologique In vitro Ligand Modèle moléculaire Modélisation Relation structure activité Récepteur sérotoninergique 5-HT4 Synthèse chimique Butyramide dérivé Undénamide dérivé
- Keyword (en)
- Affinity Carboxamide Acetylenic compound Aliphatic compound Dimer Triazine derivatives Benzene derivatives Cyclohexane derivatives Biological fixation In vitro Ligand Molecular model Modeling Structure activity relation 5-HT4 Serotonine receptor Chemical synthesis
- Keyword (es)
- Afinidad Carboxamida Compuesto acetilénico Compuesto alifático Dímero Triazina derivado Benceno derivado Ciclohexano derivado Fijación biológica In vitro Ligando Modelo molecular Modelización Relación estructura actividad Receptor serotoninérgico 5-HT4 Síntesis química
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09C Serotoninergic system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 19055667
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm070552t 
https://dx.doi.org/10.1021/jm070552t
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