Clonal evolution in chronic lymphocytic leukemia : Acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival
- Author
- STILGENBAUER, Stephan1 ; SANDER, Sandrine1 ; BULLINGER, Lars1 ; BENNER, Axel2 ; LEUPOLT, Elke1 ; WINKLER, Dirk1 ; KRÖBER, Alexander1 ; KIENLE, Dirk1 ; LICHTER, Peter3 ; DÖHNER, Hartmut1
[1] Department of Internal Medicine III, University of Ulm, Germany
[2] Biostatistics, DKFZ Heidelberg, Germany
[3] Molecular Genetics, DKFZ Heidelberg, Germany - Source
Haematologica (Roma). 2007, Vol 92, Num 9, pp 1242-1245, 4 p ; ref : 29 ref
- ISSN
- 0390-6078
- Scientific domain
- Hematology
- Publisher
- Haematologica, Pavia
- Publication country
- Italy
- Document type
- Article
- Language
- English
- Author keyword
- CLL clonal evolution genetic instability p53
- Keyword (fr)
- Chaîne peptidique lourde Clonalité Gène TP53 Gène suppresseur tumeur Génome Hématologie Immunoglobuline Risque élevé Région variable Résistance Segment V Survie Traitement Gène p53 Instabilité génétique Leucémie lymphoïde chronique Hémopathie maligne Lymphoprolifératif syndrome
- Keyword (en)
- Heavy peptide chain Clonality TP53 Gene Tumor suppressor gene Genome Hematology Immunoglobulins High risk Variable region Resistance V segment Survival Treatment Genetic instability Chronic lymphocytic leukemia Malignant hemopathy Lymphoproliferative syndrome
- Keyword (es)
- Cadena peptídica pesada Clonalidad Gen TP53 Gen supresor tumor Genoma Hematología Inmunoglobulina Riesgo alto Región variable Resistencia Segmento V Sobrevivencia Tratamiento Inestabilidad genética Leucemia linfoidea Hemopatía maligna Linfoproliferativo síndrome
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Discipline
- Blood diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 19064184
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Access to the document
Install on your browser
DOI
10.3324/haematol.10720 
https://dx.doi.org/10.3324/haematol.10720
"O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:22:\"10.3324\/haematol.10720\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:167:\"Clonal evolution in chronic lymphocytic leukemia : Acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival\";s:9:\"\u0000*\u0000jtitle\";s:20:\"Haematologica (Roma)\";s:9:\"\u0000*\u0000stitle\";s:20:\"Haematologica (Roma)\";s:7:\"\u0000*\u0000date\";s:4:\"2007\";s:9:\"\u0000*\u0000volume\";s:2:\"92\";s:8:\"\u0000*\u0000issue\";s:1:\"9\";s:8:\"\u0000*\u0000spage\";s:4:\"1242\";s:8:\"\u0000*\u0000epage\";s:4:\"1245\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0390-6078\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:12:\"STILGENBAUER\";s:10:\"\u0000*\u0000aufirst\";s:7:\"Stephan\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:9:{i:0;s:16:\"SANDER, Sandrine\";i:1;s:15:\"BULLINGER, Lars\";i:2;s:12:\"BENNER, Axel\";i:3;s:13:\"LEUPOLT, Elke\";i:4;s:13:\"WINKLER, Dirk\";i:5;s:18:\"KR\u00d6BER, Alexander\";i:6;s:12:\"KIENLE, Dirk\";i:7;s:14:\"LICHTER, Peter\";i:8;s:16:\"D\u00d6HNER, Hartmut\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:167:\"Clonal evolution in chronic lymphocytic leukemia : Acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival\";s:8:\"\u0000*\u0000place\";s:5:\"Pavia\";s:6:\"\u0000*\u0000pub\";s:13:\"Haematologica\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"4\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Panist access
"O:12:\"IstexOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:22:\"10.3324\/haematol.10720\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:167:\"Clonal evolution in chronic lymphocytic leukemia : Acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival\";s:9:\"\u0000*\u0000jtitle\";s:20:\"Haematologica (Roma)\";s:9:\"\u0000*\u0000stitle\";s:20:\"Haematologica (Roma)\";s:7:\"\u0000*\u0000date\";s:4:\"2007\";s:9:\"\u0000*\u0000volume\";s:2:\"92\";s:8:\"\u0000*\u0000issue\";s:1:\"9\";s:8:\"\u0000*\u0000spage\";s:4:\"1242\";s:8:\"\u0000*\u0000epage\";s:4:\"1245\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0390-6078\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:12:\"STILGENBAUER\";s:10:\"\u0000*\u0000aufirst\";s:7:\"Stephan\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:9:{i:0;s:16:\"SANDER, Sandrine\";i:1;s:15:\"BULLINGER, Lars\";i:2;s:12:\"BENNER, Axel\";i:3;s:13:\"LEUPOLT, Elke\";i:4;s:13:\"WINKLER, Dirk\";i:5;s:18:\"KR\u00d6BER, Alexander\";i:6;s:12:\"KIENLE, Dirk\";i:7;s:14:\"LICHTER, Peter\";i:8;s:16:\"D\u00d6HNER, Hartmut\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:167:\"Clonal evolution in chronic lymphocytic leukemia : Acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival\";s:8:\"\u0000*\u0000place\";s:5:\"Pavia\";s:6:\"\u0000*\u0000pub\";s:13:\"Haematologica\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"4\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Istex access
"O:16:\"UnpaywallOpenUrl\":35:{s:8:\"\u0000*\u0000email\";s:27:\"assistance-portail@inist.fr\";s:6:\"\u0000*\u0000fmt\";N;s:6:\"\u0000*\u0000doi\";s:22:\"10.3324\/haematol.10720\";s:6:\"\u0000*\u0000pii\";N;s:7:\"\u0000*\u0000pmid\";N;s:9:\"\u0000*\u0000atitle\";N;s:9:\"\u0000*\u0000jtitle\";N;s:9:\"\u0000*\u0000stitle\";N;s:7:\"\u0000*\u0000date\";N;s:9:\"\u0000*\u0000volume\";N;s:8:\"\u0000*\u0000issue\";N;s:8:\"\u0000*\u0000spage\";N;s:8:\"\u0000*\u0000epage\";N;s:8:\"\u0000*\u0000pages\";N;s:7:\"\u0000*\u0000issn\";N;s:8:\"\u0000*\u0000eissn\";N;s:9:\"\u0000*\u0000aulast\";N;s:10:\"\u0000*\u0000aufirst\";N;s:9:\"\u0000*\u0000auinit\";N;s:10:\"\u0000*\u0000auinitm\";N;s:5:\"\u0000*\u0000au\";N;s:9:\"\u0000*\u0000aucorp\";N;s:7:\"\u0000*\u0000isbn\";N;s:8:\"\u0000*\u0000coden\";N;s:8:\"\u0000*\u0000genre\";N;s:7:\"\u0000*\u0000part\";N;s:9:\"\u0000*\u0000btitle\";N;s:8:\"\u0000*\u0000title\";N;s:8:\"\u0000*\u0000place\";N;s:6:\"\u0000*\u0000pub\";N;s:10:\"\u0000*\u0000edition\";N;s:9:\"\u0000*\u0000tpages\";N;s:9:\"\u0000*\u0000series\";N;s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";N;}"
Unpaywall access
"O:16:\"EuropePMCOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:22:\"10.3324\/haematol.10720\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:167:\"Clonal evolution in chronic lymphocytic leukemia : Acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival\";s:9:\"\u0000*\u0000jtitle\";s:20:\"Haematologica (Roma)\";s:9:\"\u0000*\u0000stitle\";s:20:\"Haematologica (Roma)\";s:7:\"\u0000*\u0000date\";s:4:\"2007\";s:9:\"\u0000*\u0000volume\";s:2:\"92\";s:8:\"\u0000*\u0000issue\";s:1:\"9\";s:8:\"\u0000*\u0000spage\";s:4:\"1242\";s:8:\"\u0000*\u0000epage\";s:4:\"1245\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0390-6078\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:12:\"STILGENBAUER\";s:10:\"\u0000*\u0000aufirst\";s:7:\"Stephan\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:9:{i:0;s:16:\"SANDER, Sandrine\";i:1;s:15:\"BULLINGER, Lars\";i:2;s:12:\"BENNER, Axel\";i:3;s:13:\"LEUPOLT, Elke\";i:4;s:13:\"WINKLER, Dirk\";i:5;s:18:\"KR\u00d6BER, Alexander\";i:6;s:12:\"KIENLE, Dirk\";i:7;s:14:\"LICHTER, Peter\";i:8;s:16:\"D\u00d6HNER, Hartmut\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:167:\"Clonal evolution in chronic lymphocytic leukemia : Acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival\";s:8:\"\u0000*\u0000place\";s:5:\"Pavia\";s:6:\"\u0000*\u0000pub\";s:13:\"Haematologica\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"4\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Europe PubMed Central access
"O:12:\"ArXivOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:22:\"10.3324\/haematol.10720\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:167:\"Clonal evolution in chronic lymphocytic leukemia : Acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival\";s:9:\"\u0000*\u0000jtitle\";s:20:\"Haematologica (Roma)\";s:9:\"\u0000*\u0000stitle\";s:20:\"Haematologica (Roma)\";s:7:\"\u0000*\u0000date\";s:4:\"2007\";s:9:\"\u0000*\u0000volume\";s:2:\"92\";s:8:\"\u0000*\u0000issue\";s:1:\"9\";s:8:\"\u0000*\u0000spage\";s:4:\"1242\";s:8:\"\u0000*\u0000epage\";s:4:\"1245\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0390-6078\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:12:\"STILGENBAUER\";s:10:\"\u0000*\u0000aufirst\";s:7:\"Stephan\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:9:{i:0;s:16:\"SANDER, Sandrine\";i:1;s:15:\"BULLINGER, Lars\";i:2;s:12:\"BENNER, Axel\";i:3;s:13:\"LEUPOLT, Elke\";i:4;s:13:\"WINKLER, Dirk\";i:5;s:18:\"KR\u00d6BER, Alexander\";i:6;s:12:\"KIENLE, Dirk\";i:7;s:14:\"LICHTER, Peter\";i:8;s:16:\"D\u00d6HNER, Hartmut\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:167:\"Clonal evolution in chronic lymphocytic leukemia : Acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival\";s:8:\"\u0000*\u0000place\";s:5:\"Pavia\";s:6:\"\u0000*\u0000pub\";s:13:\"Haematologica\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"4\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
arXiv access
