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Rapid HPLC analysis of the antiepileptic lamotrigine and its metabolites in human plasma

Author
ADDOLORATA SARACINO, Maria1 ; BUGAMELLI, Francesca1 ; CONTI, Matteo2 ; AMORE, Mario3 ; AUGUSTA RAGGI, Maria1
[1] Laboratory ofPharmaco-Toxicological Analysis, Department of Pharmaceutical Sciences, Faculty of Pharmacy, Alma Mater Studiorum, University of Bologna, Bologna, Italy
[2] Laboratory of Clinical Pharmacology and Toxicology, Hospital of Ravenna Santa Maria delle Croci, Ravenna, Italy
[3] Department of Neurosciences, Psychiatric Division, Faculty of Medicine and Surgery, University of Parma, Parma, Italy
Source

Journal of separation science. 2007, Vol 30, Num 14, pp 2249-2255, 7 p ; ref : 22 ref

ISSN
1615-9306
Scientific domain
Biochemistry, molecular biology, biophysics; Analytical chemistry; Pharmacology drugs
Publisher
Wiley, Weinheim
Publication country
Germany
Document type
Article
Language
English
Author keyword
Biological fluids DAD detection Lamotrigine Liquid chromatography Metabolites
Keyword (fr)
Analyse chimique Analyse quantitative Anticonvulsivant Chromatographie HPLC Chromatographie phase inverse Détecteur UV Glucuroconjugué Homme Lamotrigine Liquide biologique Malade Mesure simultanée Métabolite Plasma sanguin Réseau diode Sang Validation Triazine dérivé
Keyword (en)
Chemical analysis Quantitative analysis Anticonvulsant HPLC chromatography Reversed phase chromatography Ultraviolet detector Glucuroconjugate Human Lamotrigine Biological fluid Patient Simultaneous measurement Metabolite Blood plasma Diode array Blood Validation Triazine derivatives
Keyword (es)
Análisis químico Análisis cuantitativo Anticonvulsivante Cromatografía HPLC Cromatografía fase inversa Detector UV Glucuroconjugado Hombre Lamotrigina Líquido biológico Enfermo Medición simultánea Metabolito Plasma sanguíneo Red diodo Sangre Validación Triazina derivado
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
19070903

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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