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Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma : Combination therapy improves time to progression

Author
ORLOWSKI, Robert Z; NAGLER, Arnon; SPICKA, Ivan; SUTHERLAND, Heather J; SUVOROV, Alexander N; ZHUANG, Sen H; PAREKH, Trilok; LIANG XIU; ZHILONG YUAN; RACKOFF, Wayne; HAROUSSEAU, Jean-Luc; SONNEVELD, Pieter; BLADE, Joan; HAJEK, Roman; SPENCER, Andrew; SAN MIGUEL, Jesus; ROBAK, Tadeusz; DMOSZYNSKA, Anna; HORVATH, Noemi
[1] University of North Carolina at Chapel Hill, Chapel Hill, NC, United States
[2] Chaim Sheba Medical Center, Tel Hashomer, Israel
[3] Erasmus MC, Rotterdam, Netherlands
[4] Hospital Clinic I Provincial, Barcelona, Spain
[5] Interni Hematoonkologická klinika Fakultní Brno, Brno, Czech Republic
[6] General Faculty Hospital, Prague, Czech Republic
[7] Alfred Hospital, Melbourne, Australia
[8] Institute of Medicine and Veterinary Science, Adelaide, Australia
[9] Hospital Universitario de Salamanca, Centro de Investigación del Cáncer-IBMCC (CSIC-USAL), Spain
[10] Medical University of Lodz, Lodz, Poland
[11] Medical University of Lublin, Lublin, Poland
[12] University of British Columbia, Vancouver, Canada
[13] First Republican Clinical Hospital of Udmurtia, Izhevsk, Russian Federation
[14] Johnson & Johnson Pharmaceutical Research & Development LLC, Raritan, NJ, United States
[15] University Hospital Hotel-Dieu, Nantes, France
Source

Journal of clinical oncology. 2007, Vol 25, Num 25, pp 3892-3901, 10 p ; ref : 26 ref

ISSN
0732-183X
Scientific domain
Medical oncology
Publisher
Lippincott Williams & Wilkins, Baltimore, MD
Publication country
United States
Document type
Article
Language
Russian
Keyword (fr)
Anticancéreux Bortézomib Cancérologie Doxorubicine Essai clinique phase III Etude comparative Forme pégylée Liposome Myélome Randomisation Récidive Résistance traitement Traitement associé Acide boronique Inhibiteur de la topoisomérase II Inhibiteur du protéasome Analogue Anthracyclines DNA topoisomerase (ATP-hydrolysing) Dipeptide Enzyme Hémopathie maligne Immunoglobulinopathie Immunopathologie Inhibiteur enzyme Isomerases Lymphoprolifératif syndrome
Keyword (en)
Antineoplastic agent Bortezomib Cancerology Doxorubicin Phase III trial Comparative study Pegylated form Liposome Myeloma Randomization Relapse Treatment resistance Combined treatment Analog Anthracyclins DNA topoisomerase (ATP-hydrolysing) Dipeptides Enzyme Malignant hemopathy Immunoglobulinopathy Immunopathology Enzyme inhibitor Isomerases Lymphoproliferative syndrome
Keyword (es)
Anticanceroso Bortezomib Cancerología Doxorubicina Ensayo clínico fase III Estudio comparativo Forma pegilada Liposoma Mieloma Aleatorización Recaida Resistencia tratamiento Tratamiento asociado Análogo Antraciclinas DNA topoisomerase (ATP-hydrolysing) Dipéptido Enzima Hemopatía maligna Inmunoglobulinopatía Inmunopatología Inhibidor enzima Isomerases Linfoproliferativo síndrome
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B06 Immunopathology / 002B06D Immunodeficiencies. Immunoglobulinopathies / 002B06D02 Immunoglobulinopathies

Discipline
Immunopathology Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
19075409

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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