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Interspecies prediction of human drug clearance based on scaling data from one or two animal species

Author
HUADONG TANG1 ; HUSSAIN, Azher1 ; LEAL, Mauricio1 ; MAYERSOHN, Michael2 ; FLUHLER, Eric1
[1] Bioanalytical R&D, Drug Safety and Metabolism, Wyeth Research, Pearl River, New York, United States
[2] Department of Pharmaceutical Sciences, College of Pharmacy, the University of Arizona, Tucson, Arizona, United States
Source

Drug metabolism and disposition. 2007, Vol 35, Num 10, pp 1886-1893, 8 p ; ref : 1/2 p

CODEN
DMDSAI
ISSN
0090-9556
Scientific domain
Pharmacology drugs
Publisher
American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Animal Clairance Espèce Facteur prédictif Homme Médicament Prédiction Pharmacocinétique
Keyword (en)
Animal Clearance Species Predictive factor Human Drug Prediction Pharmacokinetics
Keyword (es)
Animal Depuración Especie Factor predictivo Hombre Medicamento Predicción Farmacocinética
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
19112988

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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