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Combined high-resolution array-based comparative genomic hybridization and expression profiling of ETV6/RUNX1-positive acute lymphoblastic leukemias reveal a high incidence of cryptic Xq duplications and identify several putative target genes within the commonly gained region

Author
LILLJEBJÖRN, H1 ; HEIDENBLAD, M1 ; NILSSON, B1 ; LASSEN, C1 ; HORVAT, A1 ; HELDRUP, J2 ; BEHRENDTZ, M3 ; JOHANSSON, B1 ; ANDERSSON, A1 ; FIORETOS, T1
[1] Department of Clinical Genetics, Lund University Hospital, Lund, Sweden
[2] Department of Pediatrics, Lund University Hospital, Lund, Sweden
[3] Department of Pediatrics, Linkoping University Hospital, Linkoping, Sweden
Source

Leukemia. 2007, Vol 21, Num 10, pp 2137-2144, 8 p ; ref : 35 ref

CODEN
LEUKED
ISSN
0887-6924
Scientific domain
Medical oncology; Hematology
Publisher
Nature Publishing, London
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
ETV6/RUNX1 SPANXB array CGH expression profiling
Keyword (fr)
Ciblage Cryptique Duplication Epidémiologie Expression génique Génétique Haute résolution Hybridation génomique comparative Hématologie Incidence Leucémie aiguë Gène AML1 Gène ETV6 Hémopathie maligne lymphoïde Leucémie aiguë lymphoblastique Profil d'expression génique Technique CGH array Hémopathie maligne Lymphoprolifératif syndrome
Keyword (en)
Targeting Cryptic Duplication Epidemiology Gene expression Genetics High resolution Comparative genomic hybridization Hematology Incidence Acute leukemia Lymphoid neoplasm Acute lymphocytic leukemia Gene expression profile Array-based Comparative Genomic Hybridisation Malignant hemopathy Lymphoproliferative syndrome
Keyword (es)
Blancado Críptico Duplicación Epidemiología Expresión genética Genética Alta resolucion Hibridación genómica comparativa Hematología Incidencia Leucemia aguda Leucemia aguda linfoblástica Perfil de expresión genética Hemopatía maligna Linfoproliferativo síndrome
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis

Discipline
Blood diseases
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
19133245

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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