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Combined tipranavir and enfuvirtide use associated with higher plasma tipranavir concentrations but not with increased hepatotoxicity : sub-analysis from RESIST

Author
RAFFI, Francois1 ; BATTEGAY, Manuel2 ; RUSCONI, Stefano3 ; OPRAVIL, Milos4 ; BLICK, Gary5 ; STEIGBIGEL, Roy T6 ; KRAFT, Michael7 ; NEUBACHER, Dietmar8 ; SABO, John P9
[1] University of Nantes, Nantes, France
[2] Division of Infectious Diseases and Hospital Epidemiology, University Hospital, Basel, Switzerland
[3] Sezione di Malattie Infettive e Immunopatologia, Dipartimento di Scienze Cliniche 'Luigi Sacco', Universita degli Studi, Milan, Italy
[4] Division of Infectious Diseases, University Hospital, Zurich, Switzerland
[5] Circle Medical LLC, Norwalk, Connecticut, United States
[6] Division of Infectious Diseases, Stony Brook University Medical Center, New York, United States
[7] Boehringer Ingelheim, Ingelheim, Germany
[8] Boehringer Ingelheim Pharma GmbH and Co. KG, Ingelheim, Germany
[9] Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, Connecticut, United States
Source

AIDS (London). 2007, Vol 21, Num 14, pp 1977-1980, 4 p ; ref : 6 ref

ISSN
0269-9370
Scientific domain
Immunology, immunopathology, allergology; Microbiology, infectious diseases
Publisher
Lippincott Williams & Wilkins, Hagerstown, MD
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Antirétroviral Antiviral Concentration Enfuvirtide Foie pathologie Hépatotoxicité Plasma sanguin Ritonavir Symptomatologie Tipranavir Toxicité Inhibiteur de fusion Appareil digestif pathologie Composé non peptide Enzyme Hydrolases Inhibiteur enzyme Inhibiteur protease Peptidases Peptide
Keyword (en)
Antiretroviral agent Antiviral Concentration Enfuvirtide Hepatic disease Hepatotoxicity Blood plasma Ritonavir Symptomatology Tipranavir Toxicity Digestive diseases Non peptide compound Enzyme Hydrolases Enzyme inhibitor Protease inhibitor Peptidases Peptides
Keyword (es)
Antiretroviral Antiviral Concentración Enfuvirtida Hígado patología Hepatotoxicidad Plasma sanguíneo Ritonavir Sintomatología Tipranavir Toxicidad Aparato digestivo patología Compuesto no péptido Enzima Hydrolases Inhibidor enzima Inhibidor proteasa Peptidases Péptido
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S05 Antiviral agents

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02U Drug toxicity and drugs side effects treatment / 002B02U04 Toxicity: digestive system

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05C Viral diseases / 002B05C02 Human viral diseases / 002B05C02D Viral diseases of the lymphoid tissue and the blood. Aids

Discipline
Drugs toxicity and drug intoxications Infectious pathology Pharmacological treatments Toxicology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
19135574

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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