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Rapid doxorubicin efflux from the nucleus of drug-resistant cancer cells following extracellular drug clearance : Intracellular delivery

Author
CHEN, Vivien Y1 ; POSADA, Maria M1 ; LILI ZHAO1 ; ROSANIA, Gus R1
[1] Department of Pharmaceutical Sciences, University of Michigan College of Pharmacy, 428 Church St, Ann Arbor, MI 48109, United States
Source

Pharmaceutical research. 2007, Vol 24, Num 11, pp 2156-2167, 12 p ; ref : 40 ref

CODEN
PHREEB
ISSN
0724-8741
Scientific domain
Pharmacology drugs
Publisher
Springer, New York, NY
Publication country
United States
Document type
Article
Language
English
Author keyword
cellular pharmacokinetics doxorubicin drug delivery drug resistance drug sequestration drug targeting multivesicular body
Keyword (fr)
Absorption Antibiotique Anticancéreux Cellule tumorale Ciblage Cible Clairance Diffusion Doxorubicine In vitro Membrane plasmique Pharmacocinétique Résistance Technologie pharmaceutique Inhibiteur de la topoisomérase II Anthracyclines DNA topoisomerase (ATP-hydrolysing) Enzyme Inhibiteur enzyme Isomerases
Keyword (en)
Absorption Antibiotic Antineoplastic agent Tumor cell Targeting Target Clearance Diffusion Doxorubicin In vitro Plasma membrane Pharmacokinetics Resistance Pharmaceutical technology Anthracyclins DNA topoisomerase (ATP-hydrolysing) Enzyme Enzyme inhibitor Isomerases
Keyword (es)
Absorción Antibiótico Anticanceroso Célula tumoral Blancado Blanco Depuración Difusión Doxorubicina In vitro Membrana plasmática Farmacocinética Resistencia Tecnología farmacéutica Antraciclinas DNA topoisomerase (ATP-hydrolysing) Enzima Inhibidor enzima Isomerases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects

Discipline
General pharmacology Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
19167368

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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