Synthesis of novel anilinoquinolines as c-fms inhibitors
- Author
- SMALLEY, Terrence L1 ; CHAMBERLAIN, Stanley D1 ; MILLS, Wendy Y1 ; MUSSO, David L1 ; RANDHAWA, Sab A1 ; RAY, John A1 ; SAMANO, Vicente1 ; FRICK, Lloyd1
[1] GlaxoSmithKline, Inc., Five Moore Drive, Research Triangle Park, NC 27709, United States - Source
Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 22, pp 6257-6260, 4 p ; ref : 9 ref
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Inflammation Inhibitors Kinase
- Keyword (fr)
- Amine aromatique Animal Cytokine Dérivé de l'aniline Dérivé de la quinoléine Facteur croissance Facteur stimulant colonie macrophage Fluor Composé organique In vitro Inflammation Inhibiteur Pharmacocinétique Rat Relation structure activité Récepteur facteur croissance Synthèse chimique Transduction signal Transferases Voie intraveineuse Quinoléine-3-carboxamide(4-[4-fluoroanilino]-7-[4-mésylphényl]) Receptor protein-tyrosine kinase Enzyme Mammalia Rodentia Vertebrata
- Keyword (en)
- Aromatic amine Animal Cytokine Aniline derivatives Quinoline derivatives Growth factor Macrophage colony stimulating factor Fluorine Organic compounds In vitro Inflammation Inhibitor Pharmacokinetics Rat Structure activity relation Growth factor receptor Chemical synthesis Signal transduction Transferases Intravenous administration Enzyme Mammalia Rodentia Vertebrata
- Keyword (es)
- Amina aromática Animal Citoquina Anilina derivado Quinolina derivado Factor crecimiento Factor estimulante colonia macrófago Fluor Compuesto orgánico In vitro Inflamación Inhibidor Farmacocinética Rata Relación estructura actividad Receptor factor crecimiento Síntesis química Transducción señal Transferases Vía intravenosa Enzima Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02L Bones, joints and connective tissue. Antiinflammatory agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 19175305
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2007.09.009 
https://dx.doi.org/10.1016/j.bmcl.2007.09.009
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