Simultaneous determination of busulphan in plasma samples by liquid chromatography-electrospray ionization mass spectrometry utilizing microextraction in packed syringe (MEPS) as on-line sample preparation method
- Author
- ABDEL-REHIM, Mohamed1 2 ; HASSAN, Zuzana3 4 ; SKANSEM, Patrik5 ; HASSAN, Moustapha
[1] Department of DMPK and Bioanalysis AstraZeneca R&D Södertälje, Södertälje, Sweden
[2] Department of Chemistry, Karlstad University, Karlstad, Sweden
[3] Experimental Cancer Medicine, Clinical Research Centre, Novum Karolinska University Hospital, Huddine, Sweden
[4] Department of Laboratory Medicine, Karolinska Institutet, Sweden
[5] Department of DMPK and Bioanalysis, AstraZeneca R&D Södertälje Södertälje, Sweden - Source
Journal of liquid chromatography & related technologies. 2007, Vol 30, Num 17-20, pp 3029-3041, 13 p ; ref : 29 ref
- CODEN
- JLCTFC
- ISSN
- 1082-6076
- Scientific domain
- Biochemistry, molecular biology, biophysics; Analytical chemistry
- Publisher
- Taylor & Francis, Colchester
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Busulfan LC-MS/MS MEPS Pharmacokinetics TDM
- Keyword (fr)
- Acide sulfonique Analyse chimique Analyse quantitative Analyse trace Busulfan Chromatographie HPLC Electrospray Enrichissement chimique Homme Liquide biologique Malade Mesure simultanée Microextraction phase solide Microméthode Méthode couplée Pharmacocinétique Plasma sanguin Préparation échantillon Sang Seringue Spectrométrie masse tandem Spectrométrie masse Suivi thérapeutique pharmacologique Validation LC MS MS Acide alcanesulfonique Agent alkylant Alcanediol Anticancéreux
- Keyword (en)
- Sulfonic acid Chemical analysis Quantitative analysis Trace analysis Busulfan HPLC chromatography Electrospray Chemical enrichment Human Biological fluid Patient Simultaneous measurement Solid phase microextraction Microassay Coupled method Pharmacokinetics Blood plasma Sample preparation Blood Syringe Mass spectrometry MS/MS Mass spectrometry Therapeutic drug monitoring Validation Alkanesulfonic acid Alkylating agent Alkanediol Antineoplastic agent
- Keyword (es)
- Acido sulfónico Análisis químico Análisis cuantitativo Análisis huella Busulfano Cromatografía HPLC Electrospray Enriquecimiento químico Hombre Líquido biológico Enfermo Medición simultánea Microextracción fase sólida Micrométodo Método acoplado Farmacocinética Plasma sanguíneo Preparación muestreo Sangre Seringa Espectrometría masa en tándem Espectrometría masa Monitorización farmacoterapéutica Validación Acido alcanosulfónico Agente alquilante Alcanodiol Anticanceroso
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 19209464
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1080/10826070701632337 
https://dx.doi.org/10.1080/10826070701632337
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