A switch from prohormone convertase (PC)-2 to PC 1/3 expression in transplanted α-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis in mice
- Author
- WIDEMAN, Rhonda D1 ; COVEY, Scott D1 ; WEBB, Gene C2 ; DRUCKER, Daniel J3 ; KIEFFER, Timothy J1 4
[1] Department of Cellular and Physiological Sciences, Laboratory of Molecular and Cellular Medicine, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada
[2] Department of Medi cine, University of Chicago, Chicago, Illinois, United States
[3] Department of Medicine, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Banting and Best Diabetes Centre, University of Toronto, Toronto, Ontario, Canada
[4] Department of Surgery, Laboratory of Molecular and Cellular Medicine, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada - Source
Diabetes (New York, NY). 2007, Vol 56, Num 11, pp 2744-2752, 9 p ; ref : 45 ref
- CODEN
- DIAEAZ
- ISSN
- 0012-1797
- Scientific domain
- Endocrinology; Nutrition, obesity, metabolic disorders
- Publisher
- American Diabetes Association, Alexandria, VA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Diabète Glucose Homéostasie Proglucagon Prohormone Souris Transplantation Endocrinopathie Mammalia Rodentia Vertebrata
- Keyword (en)
- Animal Diabetes mellitus Glucose Homeostasis Proglucagon Prohormone Mouse Transplantation Endocrinopathy Mammalia Rodentia Vertebrata
- Keyword (es)
- Animal Diabetes Glucosa Homeostasis Proglucagón Prohormona Ratón Trasplantación Endocrinopatía Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance
- Discipline
- Endocrinopathies
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 19214961
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.2337/db07-0563 
https://dx.doi.org/10.2337/db07-0563
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