Enzymology of the reductive bioactivation of SR 4233 : a novel benzotriazine DI-N-oxide hypoxic cell cytotoxin
- Author
- WALTON, M. I; WORKMAN, P
MRC clin. oncology , radiotherapeutics unit, Cambridge CB2 2QH, United Kingdom - Source
Biochemical pharmacology. 1990, Vol 39, Num 11, pp 1735-1742, 8 p ; ref : 34 ref
- CODEN
- BCPCA6
- ISSN
- 0006-2952
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs; Physiology, morphology
- Publisher
- Elsevier Science, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Anticancéreux Appareil digestif Cellule tumorale Culture cellulaire Cytochrome P450 Enzyme Foie In vitro Microsome Métabolisme Reductase Réduction chimique Souris 1,2,4-benzotriazine(«3»-amino) «1,4»-dioxyde SR 4233 SR 4317 Mammalia Rodentia Vertebrata
- Keyword (en)
- Animal Antineoplastic agent Digestive system Tumor cell Cell culture Cytochrome P450 Enzyme Liver In vitro Microsome Metabolism Reductase Chemical reduction Mouse Mammalia Rodentia Vertebrata
- Keyword (es)
- Animal Anticanceroso Aparato digestivo Célula tumoral Cultivo celular Citocromo P450 Enzima Hígado In vitro Microsoma Metabolismo Reductase Reducción química Ratón Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 19278960
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/0006-2952(90)90119-6 
https://dx.doi.org/10.1016/0006-2952(90)90119-6
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