A phosphorylated prodrug for the inhibition of Pin1
- Author
- SONG ZHAO1 ; ETZKORN, Felicia A1
[1] Department of Chemistry, Virginia Tech, Blacksburg, VA 24061-0212, United States - Source
Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 23, pp 6615-6618, 4 p ; ref : 31 ref
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Bis-pivaloyloxymethyl (POM) Cell permeability Cis-proline isostere Inhibitor Peptidyl-prolyl isomerase Pin1
- Keyword (fr)
- Activité biologique Aminoamide Cellule tumorale Cytotoxicité Dérivé de l'indole Dérivé du cyclopentane Homme In vitro Inhibiteur enzyme Lignée cellulaire Ovaire Peptidylprolyl isomerase Perméabilité cellulaire Phosphate organique Phosphore Composé organique Proline Promédicament Synthèse chimique α-Aminoacide Cyclopentane-1-carboxamide(2-[3-(bis[pivaloylméthoxy]phosphoryloxy)-2-(fluorén-9-ylméthoxycarbonylamino)propylidène]-N-[2-(indol-3-yl)éthyl]) Lignée A2780 Enzyme Isomerases cis-trans-Isomerases
- Keyword (en)
- Biological activity Aminoamide Tumor cell Cytotoxicity Indole derivatives Cyclopentane derivatives Human In vitro Enzyme inhibitor Cell line Ovary Peptidylprolyl isomerase Cell permeability Organic phosphate Phosphorus Organic compounds Proline Prodrug Chemical synthesis α-Aminoacid Enzyme Isomerases cis-trans-Isomerases
- Keyword (es)
- Actividad biológica Aminoamida Célula tumoral Citotoxicidad Indol derivado Ciclopentano derivado Hombre In vitro Inhibidor enzima Línea celular Ovario Peptidylprolyl isomerase Permeabilidad celular Fosfato orgánico Fósforo Compuesto orgánico Prolina Promedicamento Síntesis química α-Aminoácido Enzima Isomerases cis-trans-Isomerases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 19372348
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2007.09.073 
https://dx.doi.org/10.1016/j.bmcl.2007.09.073
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