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Amyloid-β precursor-like protein APLP1 is a novel p53 transcriptional target gene that augments neuroblastoma cell death upon genotoxic stress

Author
TANG, X1 ; MILYAVSKY, M1 ; GOLDFINGER, N1 ; ROTTER, V1
[1] Department of Molecular Cell Biology, The Weizmann Institute of Science, Rehovot, Israel
Source

Oncogene (Basingstoke). 2007, Vol 26, Num 52, pp 7302-7312, 11 p ; ref : 1 p.1/4

ISSN
0950-9232
Scientific domain
Cell biology, histology; Medical oncology; Genetics
Publisher
Nature Publishing, Basingstoke
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
APLP1 apoptosis neuroblastoma and Alzheimer's disease p53 senescence transcription
Keyword (fr)
Amyloïde Apoptose Carcinogenèse Démence d'Alzheimer Gène TP53 Gène suppresseur tumeur Génotoxicité Mort cellulaire Neuroblastome Protéine Stress Sénescence Transcription Cancer Maladie dégénérative Pathologie de l'encéphale Pathologie du système nerveux central Pathologie du système nerveux sympathique Pathologie du système nerveux Toxicité Tumeur maligne
Keyword (en)
Amyloid Apoptosis Carcinogenesis Alzheimer disease TP53 Gene Tumor suppressor gene Genotoxicity Cell death Neuroblastoma Protein Stress Senescence Transcription Cancer Degenerative disease Cerebral disorder Central nervous system disease Autonomic neuropathy Nervous system diseases Toxicity Malignant tumor
Keyword (es)
Amiloide Apoptosis Carcinogénesis Demencia Alzheimer Gen TP53 Gen supresor tumor Genotoxicidad Muerte celular Neuroblastoma Proteína Estrés Senescencia Transcripción Cáncer Enfermedad degenerativa Encéfalo patología Sistema nervosio central patología Sistema nervioso simpático patología Sistema nervioso patología Toxicidad Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04C Molecular genetics / 002A04C05 Transcription. Transcription factor. Splicing. Rna processing

Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17E Tumors of the nervous system. Phacomatoses

Discipline
Molecular and cell biology Neurology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
19376272

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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