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A novel steroidal selective steroid sulfatase inhibitor KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells in vitro and in animal models

Author
ISHIDA, Hiroyuki1 ; NAKATA, Taisuke1 ; LI, Pui-Kai2 ; KUWABARA, Takashi1 ; AKINAGA, Shiro1 ; SUZUKI, Masayo1 ; SHIOTSU, Yukimasa1 ; TANAKA, Hideyuki1 ; SATO, Natsuko1 ; TERASAKI, Yoko1 ; TAKEBAYASHI, Miho1 ; ANAZAWA, Hideharu1 ; MURAKATA, Chikara1
[1] Pharmaceutical Research Center, Kyowa Hakko Kogyo Co., Ltd, 1188 Shimotogari, Sunto-gun, Nagaizumi-cho, Shizuoka 4118731, Japan
[2] College of Pharmacy, The Ohio State University, Columbus, OH, United States
Source

Breast cancer research and treatment. 2007, Vol 106, Num 2, pp 215-227, 13 p ; ref : 55 ref

CODEN
BCTRD6
ISSN
0167-6806
Scientific domain
Medical oncology; Obstetrics, gynecology, andrology; Pharmacology drugs
Publisher
Springer, Dordrecht
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Breast cancer Inhibitor Steroid sulfatase
Keyword (fr)
Arylsulfatase Cancer du sein Cellule tumorale Croissance In vitro Inhibiteur Modèle animal Oestrogène Stéroïde Tumeur maligne Cancer Enzyme Esterases Hormone ovarienne Hormone stéroïde sexuelle Hydrolases Pathologie de la glande mammaire Sulfuric ester hydrolases
Keyword (en)
Arylsulfatase Breast cancer Tumor cell Growth In vitro Inhibitor Animal model Estrogen Steroid Malignant tumor Cancer Enzyme Esterases Ovarian hormone Sex steroid hormone Hydrolases Mammary gland diseases Sulfuric ester hydrolases
Keyword (es)
Arylsulfatase Cáncer del pecho Célula tumoral Crecimiento In vitro Inhibidor Modelo animal Estrógeno Esteroide Tumor maligno Cáncer Enzima Esterases Hormona ovárica Hormona esteroide sexual Hydrolases Glándula mamaria patología Sulfuric ester hydrolases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20E Mammary gland diseases / 002B20E02 Tumors

Discipline
Gynecology. Andrology. Obstetrics
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
19439515

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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