Determination of the oral platelet aggregation inhibitor Sibrafiban® in rat, dog, and human plasma utilising HPLC-column switching combined with turbo ion spray single quadrupole mass spectrometry
- Author
- TIMM, U1 ; BIRNBÖCK, H1 ; ERDIN, R1 ; HOPFGARTNER, G1 ; ZUMBRUNNEN, R1
[1] F. Hoffmann-La Roche Ltd., Pharmaceuticals Division, PRNK, 68/117a, 4070 Basel, Switzerland - Source
Journal of pharmaceutical and biomedical analysis. 1999, Vol 21, Num 1, pp 151-163 ; ref : 7 ref
- CODEN
- JPBADA
- ISSN
- 0731-7085
- Scientific domain
- Medical laboratory techniques; Pharmacology drugs
- Publisher
- Elsevier Science, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Keyword (fr)
- Absorption Analyse quantitative Animal Chien Chromatographie HPLC Homme Inhibiteur thromboagrégation Métabolite Pharmacocinétique Plasma sanguin Promédicament Rat Simultané Spectrométrie masse Voie orale Carnivora Fissipedia Mammalia Rodentia Vertebrata
- Keyword (en)
- Absorption Quantitative analysis Animal Dog HPLC chromatography Human Antiplatelet agent Metabolite Pharmacokinetics Blood plasma Prodrug Rat Concurrent Mass spectrometry Oral administration Carnivora Fissipedia Mammalia Rodentia Vertebrata
- Keyword (es)
- Absorción Análisis cuantitativo Animal Perro Cromatografía HPLC Hombre Inhibidor tromboagregación Metabolito Farmacocinética Plasma sanguíneo Promedicamento Rata Simultáneo Espectrometría masa Vía oral Carnivora Fissipedia Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1970398
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0731-7085(99)00126-0 
https://dx.doi.org/10.1016/S0731-7085(99)00126-0
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