Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets
- Author
- RIX, Uwe1 ; HANTSCHEL, Oliver1 ; KÖCHER, Thomas1 ; SUPERTI-FURGA, Giulio1 ; DÜRNBERGER, Gerhard1 ; REMSING RIX, Lily L1 ; PLANYAVSKY, Melanie1 ; FERNBACH, Nora V1 ; KAUPE, Ines1 ; BENNETT, Keiryn L1 ; VALENT, Peter2 ; COLINGE, Jacques1
[1] Center for Molecular Medicine of the Austrian Academy of Sciences (CeMM), Vienna, Australia
[2] Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria - Source
Blood. 2007, Vol 110, Num 12, pp 4055-4063, 9 p ; ref : 47 ref
- ISSN
- 0006-4971
- Scientific domain
- Medical oncology; Hematology
- Publisher
- The Americain Society of Hematology, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux Chimiothérapie Chromosome C9 anormal Chromosome G22 anormal Chromosome Ph1 Cytogénétique Dasatinib Gène hybride Gène onc cellulaire Imatinib Inhibiteur enzyme Leucémie myéloïde chronique Nilotinib Non-specific serine/threonine protein kinase Protein-tyrosine kinase Protooncogène Protéomique Thérapeutique ciblée Translocation chromosomique Gène Abl Gène bcr Aberration chromosomique Cancer Chromosome anormal Enzyme Génétique Hémopathie maligne Inhibiteur de la tyrosine kinase Inhibiteur multikinase Syndrome myéloprolifératif Traitement Transferases
- Keyword (en)
- Antineoplastic agent Chemotherapy Abnormal chromosome C9 Abnormal chromosome G22 Philadelphia chromosome Cytogenetics Dasatinib Hybrid gene C-Onc gene Imatinib Enzyme inhibitor Chronic myelogenous leukemia Nilotinib Non-specific serine/threonine protein kinase Protein-tyrosine kinase Protooncogene Proteomics Targeted therapy Chromosome translocation Chromosomal aberration Cancer Abnormal chromosome Enzyme Genetics Malignant hemopathy Tyrosine kinase inhibitor Multikinase inhibitor Myeloproliferative syndrome Treatment Transferases
- Keyword (es)
- Anticanceroso Quimioterapia Cromosoma C9 anormal Cromosoma G22 anormal Cromosoma Ph1 Citogenética Dasatinib Gen híbrido Gen onc celular Imatinib Inhibidor enzima Leucemia mieloidea crónica Nilotinib Non-specific serine/threonine protein kinase Protein-tyrosine kinase Protooncogen Proteómica Terapéutica dirigida Translocación cromosómica Aberración cromosómica Cáncer Cromosoma anormal Enzima Genética Hemopatía maligna Inhibidor tyrosine kinase inhibidor multicinasa Mieloproliferativo síndrome Tratamiento Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Discipline
- Blood diseases Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 19876579
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1182/blood-2007-07-102061 
https://dx.doi.org/10.1182/blood-2007-07-102061
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