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mGluR7-like receptor and GABAB receptor activation enhance neurotoxic effects of N-methyl-D-aspartate in cultured mouse striatal GABAergic neurones

Author
LAFON-CAZAL, M1 2 ; VIENNOIS, G1 2 ; KUHN, R1 2 ; MALITSCHEK, B1 2 ; PIN, J.-P1 2 ; SHIGEMOTO, R2 3 ; BOCKAERT, J1 2
[1] CNRS-UPR 9023, 141 rue de la Cardonille, CCIPE, 34094 Montpellier, France
[2] Novartis Pharma AG, K125.6.08, 4002 Basel, Switzerland
[3] Department of Morphological Brain Science, Faculty of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-01, Japan
Issue title
Metabotropic Glutamate Receptors
Author (monograph)
COLLINGRIDGE, Graham L (Editor)1 ; LODGE, David (Editor)2 3
[1] Department of Anatomy, School of Medical Sciences, MRC Centre for Synaptic Plasticity, University of Bristol, University Walk, Bristol BS8 1TD, United Kingdom
[2] Eli Lilly & Co. Ltd, Lilly Corporate Centre, Indianapolis, IN, United States
[3] Lilly Research Centre, Eli Lilly & Co. Ltd, Erl Wood Manor, Windlesham, Surrey GU20 6PH, United Kingdom
Source

Neuropharmacology. 1999, Vol 38, Num 10, pp 1631-1640 ; ref : 1 p.1/2

CODEN
NEPHBW
ISSN
0028-3908
Scientific domain
Neurology; Pharmacology drugs; Psychology, psychopathology, psychiatry
Publisher
Elsevier, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Activité biologique Agoniste Aminoacide excitateur Animal Baclofène Cervelet Corps strié Encéphale Etude comparative GABA Glutamate In vitro Mort cellulaire Mécanisme action Neurone en grain Neurone gabaergique Neuroprotecteur Récepteur gabaergique Récepteur glutamate Récepteur métabotropique Souris Système nerveux central Toxicité N-méthyl-D-aspartate Sous-unité mGlu7 Encéphale pathologie Mammalia Rodentia Système nerveux pathologie Vertebrata
Keyword (en)
Biological activity Agonist Excitatory aminoacid Animal Baclofen Cerebellum Corpus striatum Brain (vertebrata) Comparative study GABA Glutamate In vitro Cell death Mechanism of action Granule neuron Gabaergic neurone Neuroprotective agent Gabaergic receptor Glutamate receptor Metabotropic receptor Mouse Central nervous system Toxicity Cerebral disorder Mammalia Rodentia Nervous system diseases Vertebrata
Keyword (es)
Actividad biológica Agonista Aminoácido excitador Animal Baclofeno Cerebelo Cuerpo estriado Encéfalo Estudio comparativo GABA Glutamato In vitro Muerte celular Mecanismo acción Neurona en grano Neurona gabaminérgica Neuroprotector Receptor gabaminérgico Receptor glutámato Receptor metabotropico Ratón Sistema nervioso central Toxicidad Encéfalo patología Mammalia Rodentia Sistema nervioso patología Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04F Cell structures and functions / 002A04F03 Cell receptors / 002A04F03C Aminoacid receptors (glycine, glutamate, gaba)

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B10 Neuroprotective agent

Discipline
Molecular and cell biology Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
1990473

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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