Effect of Propylene Glycol on Ibuprofen Absorption into Human Skin In Vivo
- Author
- HERKENNE, Christophe1 2 ; NAIK, Aarti1 2 ; KALIA, Yogeshvar N1 2 ; HADGRAFT, Jonathan3 ; GUY, Richard H1 4
[1] School of Pharmaceutical Sciences, University of Geneva, 30 quai E. Ansermet, 1211 Geneva, Switzerland
[2] Centre Pharmapeptides, Parc d'affaires International, 74160 Archamps, France
[3] The School of Pharmacy, University of London, 29/39 Brunswick Square, London WC1 N 1AX, United Kingdom
[4] Department of Pharmacy & Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom - Source
Journal of pharmaceutical sciences. 2008, Vol 97, Num 1, pp 185-197, 13 p ; ref : 40 ref
- CODEN
- JPMSAE
- ISSN
- 0022-3549
- Scientific domain
- Pharmacology drugs
- Publisher
- American Pharmaceutical Association, Washington, DC
/
Wiley, Hoboken, NJ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- dermatopharmacokinetics diffusivity partition coefficient percutaneous absorption skin solubility topical drug bioavailability
- Keyword (fr)
- Absorption Antiinflammatoire non stéroïde Biodisponibilité Coefficient partage Homme Ibuprofène In vivo Médicament Peau Pharmacocinétique Propanediol Solubilité Technologie pharmaceutique Voie externe Voie locale Voie percutanée Dérivé de l'acide arylpropionique Enzyme Inhibiteur enzyme Oxidoreductases Propriété physicochimique Prostaglandin-endoperoxide synthase
- Keyword (en)
- Absorption Non steroidal antiinflammatory agent Bioavailability Partition coefficient Human Ibuprofen In vivo Drug Skin Pharmacokinetics Propanediol Solubility Pharmaceutical technology Topical administration Local administration Percutaneous route Arylpropionic acid derivatives Enzyme Enzyme inhibitor Oxidoreductases Physicochemical properties Prostaglandin-endoperoxide synthase
- Keyword (es)
- Absorción Antiinflamatorio no esteroide Biodisponibilidad Coeficiente repartición Hombre Ibuprofeno In vivo Medicamento Piel Farmacocinética Propanodiol Solubilidad Tecnología farmacéutica Vía externa Vía local Vía percutánea Arilpropionico ácido derivado Enzima Inhibidor enzima Oxidoreductases Propiedad fisicoquímica Prostaglandin-endoperoxide synthase
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 19961789
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/jps.20829 
https://dx.doi.org/10.1002/jps.20829
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