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A phase I and pharmacokinetic study of sunitinib administered daily for 2 weeks, followed by a 1-week off period

Author
BRITTEN, Carolyn D1 ; KABBINAVAR, Fairooz1 ; HECHT, J. Randolph1 ; BELLO, Carlo L2 ; LI, Jim2 ; BAUM, Charles2 ; SLAMON, Dennis1
[1] David Geffen School of Medicine at the University of California, Los Angeles, 10945 Le Conte Ave., Suite 3360, Los Angeles, CA 90095, United States
[2] Pfizer Global Research and Development, La Jolla, CA, United States
Source

Cancer chemotherapy and pharmacology. 2008, Vol 61, Num 3, pp 515-524, 10 p ; ref : 23 ref

CODEN
CCPHDZ
ISSN
0344-5704
Scientific domain
Medical oncology; Pharmacology drugs
Publisher
Springer, Berlin
Publication country
Germany
Document type
Article
Language
English
Author keyword
Pharmacokinetics, Phase I, Solid tumors Sunitinib (SU11248; SUTENT®), Tyrosine kinase inhibitors
Keyword (fr)
Inhibiteur de la tyrosine kinase Inhibiteur enzyme Pharmacocinétique Phase solide Protein-tyrosine kinase Sunitinib Tumeur solide Cancer Enzyme Inhibiteur multikinase Transferases Tumeur maligne
Keyword (en)
Tyrosine kinase inhibitor Enzyme inhibitor Pharmacokinetics Solid phase Protein-tyrosine kinase Sunitinib Solid tumor Cancer Enzyme Multikinase inhibitor Transferases Malignant tumor
Keyword (es)
Inhibidor tyrosine kinase Inhibidor enzima Farmacocinética Fase sólida Protein-tyrosine kinase Sunitinib Tumor sólido Cáncer Enzima inhibidor multicinasa Transferases Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)

Discipline
Pharmacological treatments Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
19964214

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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