A small molecule pan-Bcl-2 family inhibitor, GX15-070, induces apoptosis and enhances cisplatin-induced apoptosis in non-small cell lung cancer cells
- Author
- JIANNONG LI1 2 ; VIALLET, Jean1 ; HAURA, Eric B3
[1] Thoracic Oncology and Experimental Therapeutics Program, H. Lee Moffitt Cancer Center and Research Institute, MRC3 East, Room 3056, 12902 Magnolia Drive, Tampa, FL 33612-9497, United States
[2] Department of Interdisciplinary Oncology, University of South Florida College of Medicine, Tampa, FL 33612, United States
[3] GeminX, Inc, Malvern, PA 19355, United States - Source
Cancer chemotherapy and pharmacology. 2008, Vol 61, Num 3, pp 525-534, 10 p ; ref : 44 ref
- CODEN
- CCPHDZ
- ISSN
- 0344-5704
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- Springer, Berlin
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Apoptosis Bcl-2 Chemotherapy GX 15-070· Lung cancer Mcl-1
- Keyword (fr)
- Anticancéreux Apoptose Bronchopulmonaire Cancer du poumon Carcinome non petite cellule bronchopulmonaire Chimiothérapie Cisplatine Gène onc cellulaire In vitro Inhibiteur Molécule petite Mort cellulaire Protooncogène Gène bcl2 Protéine MCL-1 Agent alkylant Cancer Pathologie de l'appareil respiratoire Pathologie des bronches Pathologie des poumons Platine II Complexe Traitement Tumeur maligne
- Keyword (en)
- Antineoplastic agent Apoptosis Bronchopulmonary Lung cancer non-small cell lung carcinoma Chemotherapy Cisplatin C-Onc gene In vitro Inhibitor Small molecule Cell death Protooncogene Protein MCL-1 Alkylating agent Cancer Respiratory disease Bronchus disease Lung disease Platinum II Complexes Treatment Malignant tumor
- Keyword (es)
- Anticanceroso Apoptosis Broncopulmonar Cáncer del pulmón Carcinoma no pequeňa célula bronchopulmonar Quimioterapia Cisplatino Gen onc celular In vitro Inhibidor Molécula pequeña Muerte celular Protooncogen Agente alquilante Cáncer Aparato respiratorio patología Bronquio patología Pulmón patología Platino II Complejo Tratamiento Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Discipline
- Pharmacological treatments Pulmonology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 19964215
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00280-007-0499-3 
https://dx.doi.org/10.1007/s00280-007-0499-3
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