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Multiple factors contribute to the toxicity of the aromatic retinoid TTNPB (Ro 13-7410) : Interactions with the retinoic acid receptors

Author
PIGNATELLO, M. A1 2 ; KAUFFMAN, F. C1 ; LEVIN, A. A3
[1] Laboratory of Cellular and Biochemical Toxicology, Rutgers University, Piscataway, New Jersey 08854, United States
[2] Department of Toxicology and Pathology, Hoffmann-LaRoche Inc., Nutley, New Jersey 07110, United States
[3] ISIS Pharmaceuticals, Carlsbad, California 92008, United States
Source

Toxicology and applied pharmacology. 1999, Vol 159, Num 2, pp 109-116 ; ref : 1 p.1/4

CODEN
TXAPA9
ISSN
0041-008X
Scientific domain
Pharmacology drugs; Toxicology
Publisher
Elsevier, San Diego, CA
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Etude comparative Fixation biologique In vitro Mécanisme action Protéine liaison Relation métabolisme toxicité Récepteur biologique Rétinoïde Rétinoïque acide Toxicité Tératogène Lignée JEG3 Protéine CRABP RO 13 7410 Récepteur rétinoique acide RAR
Keyword (en)
Comparative study Biological fixation In vitro Mechanism of action Binding protein Metabolism toxicity relation Biological receptor Retinoid Retinoic acid Toxicity Teratogen
Keyword (es)
Estudio comparativo Fijación biológica In vitro Mecanismo acción Proteína enlace Relación metabolismo toxicidad Receptor biológico Retinoide Retinoico ácido Toxicidad Teratogeno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02U Drug toxicity and drugs side effects treatment / 002B02U10 Miscellaneous (drug allergy, mutagens, teratogens...)

Discipline
Drugs toxicity and drug intoxications Toxicology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
1997227

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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