The Heterogeneity of Amyotrophic Lateral Sclerosis : A Possible Explanation of Treatment Failure
- Author
- BEGHI, Ettore1 ; MENNINI, Tiziana1 ; AL-CHALABI, Ammar8 ; BENDOTTI, Caterina1 ; BIGINI, Paolo1 ; LOGROSCINO, Giancarlo2 ; CHIO, Adriano3 ; HARDIMAN, Orla4 ; MITCHELL, Douglas5 ; SWINGLER, Robert6 ; TRAYNOR, Bryan J7
[1] Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
[2] Department of Epidemiology HSPH, Harvard University, Boston, United States
[3] Department of Neuroscienze, University of Torino, Italy
[4] epartment of Neurology, Beaumont Hospital and Royal College of Surgeons in Ireland, Dublin, Ireland
[5] Preston MND Care & Research Centre, Royal Preston Hospital, Preston, United Kingdom
[6] Department of Neurology, Ninewells Hospital and Medical School, Dundee, Scotland, United Kingdom
[7] Section on Developmental Genetic Epidemiology, NIMH, NIH, Bethesda, United States
[8] MRC Centre for Neurodegeneration Research, King's College London, London, United Kingdom - Source
Current medicinal chemistry. 2007, Vol 14, Num 30, pp 3185-3200, 16 p ; ref : 321 ref
- ISSN
- 0929-8673
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Bentham Science, Schiphol
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Amyotrophic lateral sclerosis biochemistry epidemiology genetics heterogeneity motor neuron disease
- Keyword (fr)
- Aminoacide excitateur Antibactérien Antibiotique Antioxydant Diagnostic Echec Epidémiologie Facteur BDNF Facteur CNTF Facteur croissance IGF1 Facteur neurotrophique Facteur risque Gène Maladie du neurone moteur Marqueur biologique Minocycline Mutation Neuropeptide Neurotrophine Sclérose latérale amyotrophique TRH Traitement Tripeptide Dérivé de la tétracycline Maladie dégénérative Pathologie de la moelle épinière Pathologie du système nerveux central Pathologie du système nerveux
- Keyword (en)
- Excitatory aminoacid Antibacterial agent Antibiotic Antioxidant Diagnosis Failure Epidemiology Brain derived neurotrophic factor Ciliary neurotrophic factor Insulin like growth factor 1 Neurotrophic factor Risk factor Gene Motor neuron disease Biological marker Minocycline Mutation Neuropeptide Neurotrophin Amyotrophic lateral sclerosis Thyrotropin releasing hormone Treatment Tripeptide Tetracycline derivatives Degenerative disease Spinal cord disease Central nervous system disease Nervous system diseases
- Keyword (es)
- Aminoácido excitador Antibacteriano Antibiótico Antioxidante Diagnóstico Fracaso Epidemiología Factor BDNF Factor neurotrófico ciliar Factor crecimiento IGF1 Factor neurotrófico Factor riesgo Gen Neurona motora enfermedad Marcador biológico Minociclina Mutación Neuropéptido Neurotrofina Esclerosis lateral amiotrófica TSH-RH Tratamiento Tripéptido Tetraciclina derivado Enfermedad degenerativa Médula espinal patología Sistema nervosio central patología Sistema nervioso patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17I Nervous system involvement in other diseases. Miscellaneous
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 19995056
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.2174/092986707782793862 
https://dx.doi.org/10.2174/092986707782793862
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