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AP2-Cre-mediated expression activation of an oncogenic PLAG1 transgene results in cavernous angiomatosis in mice

Author
VAN DYCK, Frederik1 ; SCROYEN, Ilse2 ; DECLERCQ, Jeroen1 ; SCIOT, Raf3 ; KAHN, Barbara4 ; LIJNEN, Roger2 ; VAN DE VEN, Wim J. M1
[1] Laboratory for Molecular Oncology, Department for Human Genetics, University Hospitals, University of Leuven, Herestraat 49/602, 3000 Leuven, Belgium
[2] Center for Molecular and Vascular Biology, University Hospitals, University of Leuven, Herestraat 49/602, 3000 Leuven, Belgium
[3] Department of Pathology, University Hospitals, University of Leuven, Herestraat 49/602, 3000 Leuven, Belgium
[4] Diabetes Unit, Endocrine Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Research North 348, 99 Brookline Avenue, Boston, MA 02215, United States
Source

International journal of oncology. 2008, Vol 32, Num 1, pp 33-40, 8 p ; ref : 38 ref

ISSN
1019-6439
Scientific domain
Medical oncology
Publisher
Editorial Academy of the International Journal of Oncology, Athens
Publication country
Greece
Document type
Article
Language
English
Author keyword
Igf-2 PLAG1 proto-oncogene aP2-Cre transgene cavernous angiomatosis hemangioma transgenic mice
Keyword (fr)
Angiomatose Angiome Animal transgénique Cancérologie Carcinogenèse Facteur croissance IGF2 Gène onc cellulaire Protooncogène Souris Facteur transcription AP2 Gène Plag1 Transgène Mammalia Pathologie de l'appareil circulatoire Pathologie des vaisseaux sanguins Rodentia Vertebrata
Keyword (en)
Angiomatosis Angioma Transgenic animal Cancerology Carcinogenesis Insulin like growth factor 2 C-Onc gene Protooncogene Mouse Transcription factor AP2 Plag1 gene Transgene Mammalia Cardiovascular disease Vascular disease Rodentia Vertebrata
Keyword (es)
Angiomatosis Angioma Animal transgénico Cancerología Carcinogénesis Factor crecimiento IGF2 Gen onc celular Protooncogen Ratón Mammalia Aparato circulatorio patología Vaso sanguíneo patología Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Discipline
Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
19997259

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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