Dose-dependent protein adduct formation in kidney, liver, and blood of rats and in human blood after perchloroethene inhalation
- Author
- PÄHLER, A1 ; PARKER, J2 ; DEKANT, W1
[1] Institut für Toxikologie, Universität Würzburg, Versbacher Str. 9, 97078 Würzburg, Germany
[2] United States Environmental Protection Agency, NCEA, Washington, DC 20460, United States - Source
Toxicological sciences (Print). 1999, Vol 48, Num 1, pp 5-13 ; ref : 26 ref
- CODEN
- TOSCF2
- ISSN
- 1096-6080
- Scientific domain
- Toxicology
- Publisher
- Oxford University Press, Cary, NC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Adduit moléculaire Animal Carcinogène Chromatographie immunoaffinité Comparaison interspécifique Composé organique perhalogéné Ethylène(tétrachloro) Foie Homme In vitro Liaison covalente Mécanisme action Méthode immunologique Protéine Rat Rein Relation dose réponse Sang Solvant organique Toxicité Lysine(Nε-dichloroacétyl) Lysine(Nε-trichloroacétyl) Mammalia Rodentia Vertebrata
- Keyword (en)
- Molecular adduct Animal Carcinogen Immunoaffinity chromatography Interspecific comparison Organic perhalocompound Ethylene(tetrachloro) Liver Human In vitro Covalent bond Mechanism of action Immunological method Protein Rat Kidney Dose activity relation Blood Organic solvent Toxicity Mammalia Rodentia Vertebrata
- Keyword (es)
- Producto adición molecular Animal Carcinógeno Cromatografía inmunoafinidad Comparación interespecífica Compuesto orgánico perhalogenado Etiléno (tetracloro) Hígado Hombre In vitro Enlace covalente Mecanismo acción Método inmunológico Proteína Rata Riñón Relación dosis respuesta Sangre Solvente orgánico Toxicidad Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03L Chemical and industrial products toxicology. Toxic occupational diseases / 002B03L04 Solvents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04E Carcinogenesis, carcinogens and anticarcinogens / 002B04E02 Chemical agents
- Discipline
- Toxicology Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 2005005
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1093/toxsci/48.1.5 
https://dx.doi.org/10.1093/toxsci/48.1.5
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