Neuroprotective effects of atypical D1 receptor agonist SKF83959 are mediated via D1 receptor-dependent inhibition of glycogen synthase kinase-3β and a receptor-independent anti-oxidative action
- Author
- YANG YU1 ; WANG, Jing-Ru1 ; SUN, Pei-Hua1 ; YANG GUO1 ; ZHANG, Zhang-Jin2 ; JIN, Guo-Zhang1 ; XUECHU ZHEN1
[1] State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
[2] School of Chinese Medicine, The University of Hong Kong, Hong-Kong - Source
Journal of neurochemistry. 2008, Vol 104, Num 4, pp 946-956, 11 p ; ref : 1 p.1/4
- CODEN
- JONRA9
- ISSN
- 0022-3042
- Scientific domain
- Cell biology, histology; Neurology; Physiology, morphology
- Publisher
- Blackwell, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- 3-methyl-6- chloro-7,8-hydroxy-1 -(3-methylphenyl)-2,3,4,5-tetrahydro-1 H- 3-benzazepine apoptosis dopamine receptor glycogen synthase kinase-3β neuroprotection nitric oxide
- Keyword (fr)
- Akt protein kinase Altération Antagoniste Dyskinésie Glycogen synthase kinase-3β Lipide Maladie de Parkinson Médicament Phosphatidylinositol Rat Récepteur biologique Récepteur dopaminergique D1 Récepteur dopaminergique Traitement Viabilité Enzyme Maladie dégénérative Mammalia Mouvement involontaire Pathologie de l'encéphale Pathologie du système nerveux central Pathologie du système nerveux Rodentia Syndrome extrapyramidal Transferases Trouble neurologique Vertebrata
- Keyword (en)
- Akt protein kinase Alteration Antagonist Dyskinesia Glycogen synthase kinase-3β Lipids Parkinson disease Drug Phosphatidylinositol Rat Biological receptor D1 Dopamine receptor Dopamine receptor Treatment Viability Enzyme Degenerative disease Mammalia Involuntary movement Cerebral disorder Central nervous system disease Nervous system diseases Rodentia Extrapyramidal syndrome Transferases Neurological disorder Vertebrata
- Keyword (es)
- Akt protein kinase Alteración Antagonista Disquinesia Glycogen synthase kinase-3β Lípido Parkinson enfermedad Medicamento Fosfatidilinositol Rata Receptor biológico Receptor dopaminérgico D1 Receptor dopaminérgico Tratamiento Viabilidad Enzima Enfermedad degenerativa Mammalia Movimiento involuntario Encéfalo patología Sistema nervosio central patología Sistema nervioso patología Rodentia Extrapiramidal síndrome Transferases Trastorno neurológico Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17A Nervous system (semeiology, syndromes) / 002B17A01 Nervous system as a whole
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20056117
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1111/j.1471-4159.2007.05062.x 
https://dx.doi.org/10.1111/j.1471-4159.2007.05062.x
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