Effect of Genetic Variation in the Organic Cation Transporter 1, OCT1, on Metformin Pharmacokinetics
- Author
- SHU, Y1 ; BROWN, C1 ; GIACOMINI, K. M1 ; CASTRO, R. A1 ; SHI, R. J1 ; LIN, E. T1 ; OWEN, R. P1 ; SHEARDOWN, S. A2 ; YUE, L3 ; BURCHARD, E. G1 ; BRETT, C. M4
[1] Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, California, United States
[2] GlaxoSmithKline, New Frontiers Science Park, Harlow, United Kingdom
[3] GlaxoSmithKline, Collegeville, Pennsylvania, United States
[4] Department of Anesthesiology, University of California San Francisco, San Francisco, California, United States - Source
Clinical pharmacology and therapeutics. 2008, Vol 83, Num 2, pp 273-280, 8 p ; ref : 25 ref
- CODEN
- CLPTAT
- ISSN
- 0009-9236
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Génotype Homme Hypoglycémiant Metformine Pharmacocinétique Polymorphisme Variabilité génétique Transporteur de cation organique 1 Biguanides
- Keyword (en)
- Genotype Human Hypoglycemic agent Metformin Pharmacokinetics Polymorphism Genetic variability Organic cation transporter 1 Biguanides
- Keyword (es)
- Genotipo Hombre Hipoglicemiante Metformina Farmacocinética Polimorfismo Variabilidad genética Biguanidas
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20072409
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.clpt.6100275 
https://dx.doi.org/10.1038/sj.clpt.6100275
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