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A photoswitchable ITAM peptidomimetic : Synthesis and real time surface plasmon resonance (SPR) analysis of the effects of cis-trans isomerization on binding

Author
KUIL, Joeri1 ; VAN WANDELEN, Loek T. M1 ; DE MOL, Nico J1 ; LISKAMP, Rob M. J1
[1] Department of Medicinal Chemistry and Chemical Biology, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, PO Box 80.082, 3508 TB Utrecht, Netherlands
Source

Bioorganic & medicinal chemistry. 2008, Vol 16, Num 3, pp 1393-1399, 7 p ; ref : 25 ref

ISSN
0968-0896
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier Science, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Azobenzene Conformational photoswitch FceRI ITAM SH2 Surface plasmon resonance Syk
Keyword (fr)
Activité biologique Composé azoïque Composé peptidomimétique Conformation Diazène(diphényl) Isomérisation cis trans Isomérisation Ligand Pentapeptide Peptide Phosphate organique Phosphopeptide Phosphore Composé organique Photoisomérisation Réaction photochimique Récepteur FcεRI Récepteur immunoglobuline Résonance plasmon surface Synthèse chimique Transduction signal Transferases Motif ITAM Protein-tyrosine kinases Enzyme
Keyword (en)
Biological activity Azo compound Peptidomimetic compound Conformation Azobenzene Cis trans isomerization Isomerization Ligand Pentapeptide Peptides Organic phosphate Phosphopeptide Phosphorus Organic compounds Photoisomerization Photochemical reaction FcεRI receptor Immunoglobulin receptor Surface plasmon resonance Chemical synthesis Signal transduction Transferases Immunoreceptor tyrosine based activation motif Enzyme
Keyword (es)
Actividad biológica Compuesto azoico Compuesto peptidomimético Conformación Isomerización cis trans Isomerización Ligando Pentapéptido Péptido Fosfato orgánico Fosfopéptido Fósforo Compuesto orgánico Fotoisomerización Reacción fotoquímica Receptor FcεRI Receptor immunoglobulina Síntesis química Transducción señal Transferases Enzima
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20082213

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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