Simultaneous determination of GFA and its active metabolites in human plasma by liquid chromatography electrospray ionization mass spectrometry and its application to pharmacokinetic studies
- Author
- QING HUANG1 ; WANG, Guang-Ji1 ; LIU, Lin-Sheng1 ; SUN, Jian-Guo1 ; A, Ji-Ye1 ; ZHA, Wei-Bin1 ; YING ZHANG1 ; ZHANG, Jing-Wei1 ; BEI YAN1 ; GU, Sheng-Hua1 ; REN, Hong-Can1
[1] Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210038, Jiangsu Province, China - Source
Journal of pharmaceutical and biomedical analysis. 2008, Vol 46, Num 4, pp 728-736, 9 p ; ref : 24 ref
- CODEN
- JPBADA
- ISSN
- 0731-7085
- Scientific domain
- Medical laboratory techniques; Pharmacology drugs
- Publisher
- Elsevier Science, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Guanfu alcohol-amine Guanfu base A Guanfu base I LC-MS Metabolites Pharmacokinetics
- Keyword (fr)
- Alcool Algorithme génétique Amine Analyse chimique Chromatographie phase liquide Electrospray Homme Liquide biologique Mesure simultanée Métabolite Pharmacocinétique Plasma sanguin Spectrométrie masse LC MS
- Keyword (en)
- Alcohol Genetic algorithm Amine Chemical analysis Liquid chromatography Electrospray Human Biological fluid Simultaneous measurement Metabolite Pharmacokinetics Blood plasma Mass spectrometry
- Keyword (es)
- Alcohol Algoritmo genético Amina Análisis químico Cromatografía fase líquida Electrospray Hombre Líquido biológico Medición simultánea Metabolito Farmacocinética Plasma sanguíneo Espectrometría masa
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis
- Discipline
- Analytical, structural and metabolic biochemistry General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20137167
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.jpba.2007.11.033 
https://dx.doi.org/10.1016/j.jpba.2007.11.033
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