Systematic determination of ion score cutoffs based on calculated false positive rates : application for identifying ubiquitinated proteins by tandem mass spectrometry
- Author
- VASILESCU, Julian1 ; SMITH, Jeffrey C1 ; ZWEITZIG, Daniel R2 ; DENIS, Nicholas J1 ; HAINES, Dale S2 ; FIGEYS, Daniel1
[1] Ottawa Institute of Systems Biology, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1 H 8M5, Canada
[2] Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, PA, 19140, United States - Source
Journal of mass spectrometry. 2008, Vol 43, Num 3, pp 296-304, 9 p ; ref : 40 ref
- ISSN
- 1076-5174
- Scientific domain
- Biochemistry, molecular biology, biophysics; Analytical chemistry; Organic chemistry
- Publisher
- Wiley, Chichester
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Mass spectrometry false positive rates ion score cutoffs ubiquitination
- Keyword (fr)
- Analyse chimique Analyse qualitative Chromatographie HPLC Faux positif Fragment peptidique Modification posttraductionnelle Méthode analyse Méthode couplée Méthode temps vol Peptide Piège ion Protéine Protéomique Signature spectrale Spectromètre quadripolaire LC MS MS Spectrométrie masse tandem Ubiquitine dérivé
- Keyword (en)
- Chemical analysis Qualitative analysis HPLC chromatography False positive Peptide fragment Posttranslational modification Analysis method Coupled method Time of flight method Peptides Ion trap Protein Proteomics Spectral signature Quadrupole spectrometer Tandem mass spectrometry
- Keyword (es)
- Análisis químico Análisis cualitativo Cromatografía HPLC Falso positivo Fragmento peptídico Modificación postraduccional Método análisis Método acoplado Método tiempo vuelo Péptido Trampa ión Proteína Proteómica Signatura espectral Espectrómetro cuadripolar Espectrometría masa en tándem
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry / 002A02D Proteins / 002A02D01 General aspects, investigation methods
- Discipline
- Analytical, structural and metabolic biochemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20140407
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/jms.1297 
https://dx.doi.org/10.1002/jms.1297
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