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A phase II study to determine the ability of gefitinib to reverse fluoropyrimidine resistance in metastatic colorectal cancer (the INFORM study)

Author
STEBBING, J1 ; HARRISON, M2 ; GLYNNE-JONES, R2 ; BRIDGEWATER, J3 ; PROPPER, D4
[1] Imperial College, Imperial Healthcare, NHS Trust, Fulham Palace Road, London W6 8RF, United Kingdom
[2] Department of Oncology, Mount Vernon Hospital, Northwood HA6 2RN, United Kingdom
[3] Department of Oncology, Middlesex Hospital, Royal Free and University College Medical School, Mortimer Street, London, WIT 3AA, United Kingdom
[4] Department of Medical Oncology, St Bartholomew's Hospital, West Smithfield, ECIA 7BE, London, United Kingdom
Source

British journal of cancer. 2008, Vol 98, Num 4, pp 716-719, 4 p ; ref : 3/4 p

CODEN
BJCAAI
ISSN
0007-0920
Scientific domain
Medical oncology
Publisher
Nature Publishing Group, Basingstoke
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
5-fluorouracil colorectal cancer gefitinib phase II refractory
Keyword (fr)
Anticancéreux Cancer colorectal Cancérologie Essai clinique phase II Fluorouracil Géfitinib Métastase Résistance traitement Réversibilité Stade avancé Traitement Antimétabolite Cancer Dérivé de la fluoropyrimidine Dérivé de la pyrimidine Dérivé de la quinazoline Enzyme Inhibiteur de la tyrosine kinase Inhibiteur enzyme Methyltransferases Pathologie de l'appareil digestif Pathologie de l'intestin Pathologie du côlon Pathologie du rectum Protein-tyrosine kinase Thymidylate synthase Transferases Tumeur maligne
Keyword (en)
Antineoplastic agent Colorectal cancer Cancerology Phase II trial Fluorouracil Gefitinib Metastasis Treatment resistance Reversibility Advanced stage Treatment Antimetabolic Cancer Fluoropyrimidine derivatives Pyrimidine derivatives Quinazoline derivatives Enzyme Tyrosine kinase inhibitor Enzyme inhibitor Methyltransferases Digestive diseases Intestinal disease Colonic disease Rectal disease Protein-tyrosine kinase Thymidylate synthase Transferases Malignant tumor
Keyword (es)
Anticanceroso Cancer de colon y recto Cancerología Ensayo clínico fase II Fluorouracilo Gefitinib Metástasis Resistencia tratamiento Reversibilidad Estadio avanzado Tratamiento Antimetabólito Cáncer Fluoropirimidina derivado Pirimidina derivado Enzima Inhibidor tyrosine kinase Inhibidor enzima Methyltransferases Aparato digestivo patología Intestino patología Colón patología Recto patología Protein-tyrosine kinase Thymidylate synthase Transferases Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B01 Tumors

Discipline
Gastroenterology. Liver. Pancreas. Abdomen Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20178596

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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