Allogeneic Granulocyte Macrophage Colony-Stimulating Factor-Secreting Tumor Immunotherapy Alone or in Sequence with Cyclophosphamide for Metastatic Pancreatic Cancer : A Pilot Study of Safety, Feasibility, and Immune Activation
- Author
- LAHERU, Dan1 ; LUTZ, Eric2 ; HEGE, Kristen3 ; JAFFEE, Elizabeth1 2 ; BURKE, James3 ; BIEDRZYCKI, Barbara1 ; SOLT, Sara2 ; ONNERS, Beth1 ; TARTAKOVSKY, Irena1 ; NEMUNAITIS, John4 ; LE, Dung1 ; SUGAR, Elizabeth1 5
[1] Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, United States
[2] Graduate Program in Immunology, The Johns Hopkins University School of Public Health, Baltimore, Maryland, United States
[3] Cell Genesys, Inc, South San Francisco, California, United States
[4] Mary Crowley Medical Research Center, Sammons Cancer Center,Texas Oncology P.A, Dallas, Texas, United States
[5] Department of Biostatistics, The Johns Hopkins University School of Public Health, Baltimore, Maryland, United States - Source
Clinical cancer research. 2008, Vol 14, Num 5, pp 1455-1463, 9 p ; ref : 40 ref
- ISSN
- 1078-0432
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux Cancer du pancréas Cyclophosphamide Facteur stimulant colonie granulocyte macrophage Faisabilité Immunostimulation Immunothérapie Métastase Stade avancé Système allogénique Toxicité Traitement Tumeur maligne Agent alkylant Cancer Dérivé de l'oxazaphosphinane Moutarde à l'azote Pathologie de l'appareil digestif Pathologie du pancréas
- Keyword (en)
- Antineoplastic agent Pancreas cancer Cyclophosphamide Granulocyte macrophage colony stimulating factor Feasibility Immunostimulation Immunotherapy Metastasis Advanced stage Allogeneic system Toxicity Treatment Malignant tumor Alkylating agent Cancer Oxazaphosphinane derivatives Nitrogen mustard Digestive diseases Pancreatic disease
- Keyword (es)
- Anticanceroso Cáncer del páncreas Ciclofosfamida Factor estimulante colonia granulocito macrófago Practicabilidad Inmunoestimulación Inmunoterapia Metástasis Estadio avanzado Sistema alogénico Toxicidad Tratamiento Tumor maligno Agente alquilante Cáncer Oxazafosfinano derivado Mostaza al nitrógeno Aparato digestivo patología Páncreas patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13C Liver. Biliary tract. Portal circulation. Exocrine pancreas / 002B13C01 Tumors
- Discipline
- Gastroenterology. Liver. Pancreas. Abdomen Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20192246
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/1078-0432.CCR-07-0371 
https://dx.doi.org/10.1158/1078-0432.CCR-07-0371
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