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Amino Acid Mutation N3481 in the Connection Subdomain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confers Multiclass Resistance to Nucleoside and Nonnucleoside Reverse Transcriptase Inhibitors

Author
HACHIYA, Atsuko1 2 ; KODAMA, Eiichi N3 ; SARAFIANOS, Stefan G4 ; SCHUCKMANN, Matthew M4 ; SAKAGAMI, Yasuko3 ; MATSUOKA, Masao3 ; TAKIGUCHI, Masafumi2 ; GATANAGA, Hiroyuki1 ; OKA, Shinichi1
[1] AIDS Clinical Center, International Medical Center of Japan, Tokyo, Japan
[2] Center for AIDS Research, Kumamoto University, Kumamoto, Japan
[3] Institute for Virus Research, Kyoto University, Kyoto, Japan
[4] Department of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Bond Life Sciences Center, Columbia, Missouri, United States
Source

Journal of virology. 2008, Vol 82, Num 7, pp 3261-3270, 10 p ; ref : 43 ref

ISSN
0022-538X
Scientific domain
Biochemistry, molecular biology, biophysics; Microbiology, infectious diseases; Virology
Publisher
American Society for Microbiology, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Composé non nucléoside Inhibiteur reverse transcriptase Mutation Nucléoside RNA-directed DNA polymerase Résistance SIDA Virologie Virus HIV1 Enzyme Immunodéficit Immunopathologie Infection Lentivirus Nucleotidyltransferases Retroviridae Transferases Virose Virus immunodéficience humaine Virus
Keyword (en)
Non nucleoside compound Reverse transcriptase inhibitor Mutation Nucleoside RNA-directed DNA polymerase Resistance AIDS Virology HIV-1 virus Enzyme Immune deficiency Immunopathology Infection Lentivirus Nucleotidyltransferases Retroviridae Transferases Viral disease Human immunodeficiency virus Virus
Keyword (es)
Compuesto no nucleósido Inhibitor reverse transcriptase Mutación Nucleósido RNA-directed DNA polymerase Resistencia SIDA Virología HIV-1 virus Enzima Inmunodeficiencia Inmunopatología Infección Lentivirus Nucleotidyltransferases Retroviridae Transferases Virosis Human immunodeficiency virus Virus
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05C Virology / 002A05C10 Miscellaneous

Discipline
Microbiology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20194473

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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