A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
- Author
- THORGEIRSSON, Thorgeir E1 ; GELLER, Frank1 ; STACEY, Simon N1 ; BERGTHORSSON, Jon T1 ; THORLACIUS, Steinunn1 ; GUDMUNDSSON, Julius1 ; JONSSON, Thorlakur1 ; JAKOBSDOTTIR, Margret1 ; SAEMUNDSDOTTIR, Jona1 ; OLAFSDOTTIR, Olof1 ; GUDMUNDSSON, Larus J1 ; BJORNSDOTTIR, Gyda1 ; SULEM, Patrick1 ; KRISTJANSSON, Kristleifur3 ; SKULADOTTIR, Halla4 ; ISAKSSON, Helgi J5 ; GUDBJARTSSON, Tomas6 ; JONES, Gregory T7 ; MUELLER, Thomas8 ; GOTTSÄTER, Anders9 ; FLEX, Andrea10 ; ABEN, Katja K. H11 12 ; DE VEGT, Femmie11 ; RAFNAR, Thorunn1 ; MULDERS, Peter F. A13 ; LSLA, Dolores14 ; VIDALL, Maria J14 ; ASIN, Laura15 ; SAEZ, Berta16 ; MURILLO, Laura17 ; BLONDAL, Thorsteinn18 ; KOLBEINSSON, Halldor19 ; STEFANSSON, Jon G19 ; HANSDOTTIR, Ingunn20 ; WISTE, Anna1 2 ; RUNARSDOTTIR, Valgerdur20 ; POLA, Roberto10 21 ; LINDBLAD, Bengt9 ; VAN RIJ, Andre M7 ; DIEPLINGER, Benjamin8 ; HALTMAYER, Meinhard8 ; MAYORDOMO, Jose. I14 15 16 ; KIEMENEY, Lambertus A11 12 13 ; MATTHIASSON, Stefan E22 ; OSKARSSON, Hogni23 ; MAGNUSSON, Kristinn P1 ; TYRFINGSSON, Thorarinn20 ; GUDBJARTSSON, Daniel F3 ; GULCHER, Jeffrey R3 ; JONSSON, Steinn24 ; THORSTEINSDOTTIR, Unnur22 3 ; KONG, Augustine3 ; STEFANSSON, Kari22 3 ; MANOLESCU, Andrei1 ; THORLEIFSSON, Gudmar1 ; STEFANSSON, Hreinn1 ; INGASON, Andres1
[1] deCODE Genetics, 101 Reykjavik, Iceland
[2] Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA 30322, United States
[3] deCODE Genetics, 101 Reykjavik, Iceland
[4] Department of Medical Oncology, Landspitali University Hospital, 101 Reykjavik, Iceland
[5] Department of Pathology, Landspitali University Hospital, 101 Reykjavik, Iceland
[6] Department of Cardiothoracic Surgery, Landspitali University Hospital, 101 Reykjavik, Iceland
[7] Department of Surgery, Dunedin School of Medicine, University of Otago, Dunedin 9054, New Zealand
[8] Department of Laboratory Medicine, Konventhospital Barmherzige Brueder, 4020 Linz, Austria
[9] Center for Vascular Diseases, University Hospital, MAS, 205 02 Malmö, Sweden
[10] Laboratory of Vascular Biology and Genetics, A. Gemelli University Hospital, Universita Cattolica del Sacro Cuore School of Medicine, 00168 Rome, Italy
[11] Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, Netherlands
[12] Comprehensive Cancer Center East, 6501 BG Nijmegen, Netherlands
[13] Department of Urology, Radboud University Nijmegen Medical Centre, 6525 GA Nijmegen, Netherlands
[14] Division of Medical Oncology, University Hospital, 5009 Zaragoza, Spain
[15] Nanotechnology Institute of Aragon, 5009 Zaragoza, Spain
[16] Health Science Institute, 5009 Zaragoza, Spain
[17] Division of Medical Oncology, Hospital Reina Sofia, 31500 Tudela, Spain
[18] Department of Lung Disease, Primary Health Care Centre, 101 Reykjavik, Iceland
[19] Department of General Adult Psychiatry, Landspitali University Hospital, 101 Reykjavik, Iceland
[20] Vogur SAA Addiction Treatment Center, 112 Reykjavik, Iceland
[21] OASI Institute for Research and Care (IRCCS), 94018 Troina (EN), Italy
[22] School of Medicine, University of Iceland, 101 Reykjavik, Iceland
[23] Therapeia, 101 Reykjavik, Iceland
[24] Department of Medicine, Landspitali University Hospital, 101 Reykjavik, Iceland - Source
Nature (London). 2008, Vol 452, Num 7187, pp 638-641, 4 p ; ref : 30 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Artériopathie oblitérante Cancer du poumon Cancérologie Epidémiologie Facteur risque Génotype Homme Nicotine Récepteur cholinergique Récepteur nicotinique Tabagisme Variabilité génétique Espagne Islande Pays-Bas Alcaloïde Cancer Génétique Pathologie de l'appareil circulatoire Pathologie de l'appareil respiratoire Pathologie des artères Pathologie des bronches Pathologie des poumons Pathologie des vaisseaux sanguins Santé publique Tumeur maligne Europe Iles Atlantiques
- Keyword (en)
- Occlusive arterial disease Lung cancer Cancerology Epidemiology Risk factor Genotype Human Nicotine Cholinergic receptor Nicotinic receptor Tobacco smoking Genetic variability Spain Iceland Netherlands Alkaloid Cancer Genetics Cardiovascular disease Respiratory disease Arterial disease Bronchus disease Lung disease Vascular disease Public health Malignant tumor Europe Atlantic Ocean Islands
- Keyword (es)
- Arteriopatía oclusiva Cáncer del pulmón Cancerología Epidemiología Factor riesgo Genotipo Hombre Nicotina Receptor colinérgico Receptor nicotínico Tabaquismo Variabilidad genética España Islandia Holanda Alcaloide Cáncer Genética Aparato circulatorio patología Aparato respiratorio patología Arteria patología Bronquio patología Pulmón patología Vaso sanguíneo patología Salud pública Tumor maligno Europa Islas Atlántico
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12B Blood and lymphatic vessels / 002B12B03 Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
- Discipline
- Cardiology. Circulatory system Pulmonology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20207150
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature06846 
https://dx.doi.org/10.1038/nature06846
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arXiv access
