A novel liposomal irinotecan formulation with significant anti-tumour activity : Use of the divalent cation ionophore A23187 and copper-containing liposomes to improve drug retention
- Author
- RAMSAY, Euan1 2 ; ALNAJIM, Jehan1 ; ANANTHA, Malathi1 ; ZASTRE, Jason1 ; HONG YAN1 ; WEBB, Murray1 ; WATERHOUSE, Dawn1 3 ; BALLY, Marcel1 3 4
[1] Department of Advanced Therapeutics, BC Cancer Agency, BC, Canada
[2] School of Pharmacy, University of Tasmania, Tasmania, Australia
[3] Faculty of Pharmaceutical Sciences, University of British Columbia, BC, Canada
[4] Department of Pathology and Laboratory Medicine, University of British Columbia, BC, Canada - Source
European journal of pharmaceutics and biopharmaceutics. 2008, Vol 68, Num 3, pp 607-617, 11 p ; ref : 63 ref
- ISSN
- 0939-6411
- Scientific domain
- Pharmacology drugs
- Publisher
- Elsevier Science, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- A23187 Copper In vivo Irinotecan Liposome
- Keyword (fr)
- Anticancéreux Cation Cuivre Formulation In vivo Irinotécan Liposome Médicament Rétention Technologie pharmaceutique Camptothécine dérivé DNA topoisomerase Enzyme Inhibiteur de la topoisomérase I Inhibiteur enzyme Isomerases
- Keyword (en)
- Antineoplastic agent Cations Copper Formulation In vivo Irinotecan Liposome Drug Retention Pharmaceutical technology Camptothecin derivatives DNA topoisomerase Enzyme Topoisomerase I inhibitor Enzyme inhibitor Isomerases
- Keyword (es)
- Anticanceroso Cation Cobre Formulación In vivo Irinotecán Liposoma Medicamento Retención Tecnología farmacéutica Camptothecin derivado DNA topoisomerase Enzima Inhibidor topoisomerase I Inhibidor enzima Isomerases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20207363
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ejpb.2007.08.011 
https://dx.doi.org/10.1016/j.ejpb.2007.08.011
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