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Anti-Inflammatory Effects of Flavonoids : Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT-1 and NF-κB Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF-κB Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated Macrophages

Author
HÄMÄLÄINEN, Mari1 ; NIEMINEN, Riina1 ; VUORELA, Pia2 ; HEINONEN, Marina3 ; MOILANEN, Eeva1
[1] The Immunopharmacology Research Group, University of Tampere, Medical School and Tampere University Hospital, Research Unit, 33014 Tampere, Finland
[2] Department of Biochemistry and Pharmacy, Åbo Akademi University, 20520 Turku, Finland
[3] Department of Applied Chemistry and Microbiology, University of Helsinki, 00014 Helsinki, Finland
Source

Mediators of inflammation. 2007, Vol 2007, Num 1, pp 1-10, 10 p ; ref : 36 ref

ISSN
0962-9351
Scientific domain
Cell biology, histology; Immunology, immunopathology, allergology
Publisher
Hindawi, Sylvania, OH
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Activation Antiinflammatoire Biosynthèse Daidzéine Facteur transcription NFκB Facteur transcription STAT1 Flavone Flavonoïde Génistéine Kaempférol Macrophage Nitric-oxide synthase Quercétine Dérivé de l'isoflavone Enzyme Inhibiteur de la tyrosine kinase Oxidoreductases Phénols Polyphénol
Keyword (en)
Activation Antiinflammatory agent Biosynthesis Daidzein Transcription factor NFκB Transcription factor STAT1 Flavones Flavonoid Genistein Kaempferol Macrophage Nitric-oxide synthase Quercetin Isoflavone derivatives Enzyme Tyrosine kinase inhibitor Oxidoreductases Phenols Polyphenol
Keyword (es)
Activación Antiinflamatorio Biosíntesis Daidzeina Factor transcripción NFκB Factor transcripción STAT1 Flavonoide Genisteina Macrófago Nitric-oxide synthase Quercetina Enzima Inhibidor tyrosine kinase Oxidoreductases Fenoles Polifenol
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B01 General aspects

Discipline
Generalities in medical sciences
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20215178

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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