Linezolid (ZYVOX), the First Member of a Completely New Class of Antibacterial Agents for Treatment of Serious Gram-Positive Infections
- Author
- BRICKNER, Steven J1 ; BARBACHYN, Michael R2 ; HUTCHINSON, Douglas K3 ; MANNINEN, Peter R4
[1] Pfizer Global Research and Development, Groton, Connecticut 06340, United States
[2] AstraZeneca Pharmaceuticals LP, Waltham, Massachusetts 02451, United States
[3] Abbott Laboratories, Abbott Park, Illinois 60064, United States
[4] Eli Lilly and Company, Indianapolis, Indiana 46285, United States - Source
Journal of medicinal chemistry (Print). 2008, Vol 51, Num 7, pp 1981-1990, 10 p ; ref : 63 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Antibactérien Bactérie Gram positif Biodisponibilité Enterococcus faecium Infection Inhibiteur synthèse protéique Linézolide Méticilline Pharmacocinétique Pénicilline Résistance Staphylococcus aureus Streptococcus pneumoniae Synthèse chimique Traitement Vancomycine Voie orale Souche résistante méticilline Souche résistante pénicilline Souche résistante vancomycine Bactérie Dérivé de l'oxazole Dérivé de l'oxazolidinone Micrococcaceae Micrococcales Streptococcaceae
- Keyword (en)
- Biological activity Antibacterial agent Gram positive bacteria Bioavailability Enterococcus faecium Infection Protein synthesis inhibitor Linezolid Meticillin Pharmacokinetics Penicillin Resistance Staphylococcus aureus Streptococcus pneumoniae Chemical synthesis Treatment Vancomycin Oral administration Bacteria Oxazole derivatives Oxazolidinone derivative Micrococcaceae Micrococcales Streptococcaceae
- Keyword (es)
- Actividad biológica Antibacteriano Bacteria Gram positiva Biodisponibilidad Enterococcus faecium Infección Inhibidor síntesis proteica Linezolid Meticilina Farmacocinética Penicilina Resistencia Staphylococcus aureus Streptococcus pneumoniae Síntesis química Tratamiento Vancomicina Vía oral Bacteria Oxazol derivado Oxazolidinona derivado Micrococcaceae Micrococcales Streptococcaceae
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S02 Antibacterial agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20245703
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm800038g 
https://dx.doi.org/10.1021/jm800038g
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