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A sensitive and selective liquid chromatographic tandem mass spectrometric assay for simultaneous quantification of novel trioxane antimalarials in different biomatrices using sample-pooling approach for high throughput pharmacokinetic studies

Author
RAJENDRA PRATAP SINGH1 2 ; SABARINATH, S1 3 ; SHIO KUMAR SINGH1 ; RAM CHANDRA GUPTA1
[1] Pharmacokinetics & Metabolism Division, Central Drug Research Institute, Lucknow 226001, India
[2] Metabolism and Pharmacokinetics, Ranbaxy Research Laboratories, Gurgaon, India
[3] College of Pharmacy, University of Florida, Gainesville, United States
Source

Journal of chromatography. B. 2008, Vol 864, Num 1-2, pp 52-60, 9 p ; ref : 25 ref

ISSN
1570-0232
Scientific domain
Medical laboratory techniques; Pharmacology drugs
Publisher
Elsevier Science, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Biomatrices Electrospray ionization Sample pooling Tandem mass spectrometry Trioxane antimalarials
Keyword (fr)
Analyse chimique Analyse quantitative Antipaludique Antiparasitaire Electrospray Mesure simultanée Pharmacocinétique Spectrométrie masse tandem Analyse à haut débit LC MS MS Trioxane dérivé
Keyword (en)
Chemical analysis Quantitative analysis Antimalarial Parasiticide Electrospray Simultaneous measurement Pharmacokinetics Mass spectrometry MS/MS
Keyword (es)
Análisis químico Análisis cuantitativo Antipalúdico Antiparasitario Electrospray Medición simultánea Farmacocinética Espectrometría masa en tándem
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis

Discipline
Analytical, structural and metabolic biochemistry General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20258140

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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